TBR1 抗体 (AA 15-682)
Quick Overview for TBR1 抗体 (AA 15-682) (ABIN7600119)
抗原
See all TBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-682
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原理
- Anti-TBR1 Antibody Picoband®
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产品特性
- Anti-TBR1 Antibody Picoband® (ABIN7600119). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TBR1 recombinant protein (Position: K15-S682). Human TBR1 shares 99.3% amino acid (aa) sequence identity with mouse TBR1.
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anti-T-Box Brain Gene 1 (TBR1) (AA 1-108) antibody
TBR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F6 unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 1-108) antibodyTBR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 51-100) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, Pig, 豚鼠, 马, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) antibodyTBR1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) antibodyTBR1 适用: 小鼠, 大鼠 IHC, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (N-Term) antibodyTBR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 575-624) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (N-Term) antibodyTBR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Box Brain Gene 1 (TBR1) (AA 52-80) antibodyTBR1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bulfone, A., Smiga, S. M., Shimamura, K., Peterson, A., Puelles, L., Rubenstein, J. L. R. T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron 15: 63-78, 1995. 2. den Hoed, J., Sollis, E., Venselaar, H., Estruch, S. B., Deriziotis, P., Fisher, S. E. Functional characterization of TBR1 variants in neurodevelopmental disorder. Sci. Rep. 8: 14279, 2018. 3. Deriziotis, P., O'Roak, B. J., Graham, S. A., Estruch, S. B., Dimitropoulou, D., Bernier, R. A., Gerdts, J., Shendure, J., Eichler, E. E., Fisher, S. E. De novo TBR1 mutations in sporadic autism disrupt protein functions. Nature Commun. 5: 4954, 2014. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TBR1 (T-Box Brain Gene 1 (TBR1))
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别名
- TBR1
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背景
- T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene. This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
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分子量
- 74 kDa
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基因ID
- 10716
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UniProt
- Q16650
抗原
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