POT1 抗体 (AA 15-638)
Quick Overview for POT1 抗体 (AA 15-638) (ABIN7600116)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-638
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原理
- Anti-POT1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-POT1 Antibody Picoband® (ABIN7600116). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived rat POT1 recombinant protein (Position: N15-V638).
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亚型
- IgG
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anti-Protection of Telomeres 1 (POT1) (AA 250-432) antibody
POT1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 1-95) antibodyPOT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 497-634) antibodyPOT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 251-300) antibodyPOT1 适用: 人, 小鼠, 豚鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (Internal Region) antibodyPOT1 适用: 人, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (N-Term) antibodyPOT1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (AA 251-300) antibodyPOT1 适用: 人, 豚鼠, 犬, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protection of Telomeres 1 (POT1) (Middle Region) antibodyPOT1 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Cow, Pig, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL,
1. "Entrez Gene: POT1 POT1 protection of telomeres 1 homolog (S. pombe)". 2. Baumann P, Cech TR (May 2001). "Pot1, the putative telomere end-binding protein in fission yeast and humans". Science 292 (5519): 1171-5. 3. Baumann P, Podell E, Cech TR (Oct 2002). "Human Pot1 (Protection of Telomeres) Protein: Cytolocalization, Gene Structure, and Alternative Splicing". Mol Cell Biol 22 (22): 8079-87. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- Pot1
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背景
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Synonyms: Nucleoprotein TPR, Megator, NPC-associated intranuclear protein, Translocated promoter region protein, TPR
Tissue Specificity: Expressed in esophagus, ovary, liver, skin, smooth muscles, cerebrum and fetal cerebellum (at protein level). Highest in testis, lung, thymus, spleen and brain, lower levels in heart, liver and kidney.
Background: Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
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分子量
- 71 kDa
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基因ID
- 500054
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UniProt
- A0A0G231
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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