RIPK2 抗体 (AA 15-540)
Quick Overview for RIPK2 抗体 (AA 15-540) (ABIN7600113)
抗原
See all RIPK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-540
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原理
- Anti-RIP2/RIPK2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RIP2/RIPK2 Antibody Picoband® (ABIN7600113). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RIP2/RIPK2 recombinant protein (Position: Y15-M540).
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亚型
- IgG
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anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 431-540) antibody
RIPK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6F7 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 431-540) antibodyRIPK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 7F5 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 458-488), (C-Term) antibodyRIPK2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03318 unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 458-488) antibodyRIPK2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 1-294) antibodyRIPK2 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 1-540) antibodyRIPK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (AA 432-540) antibodyRIPK2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (pSer176) antibodyRIPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (N-Term) antibodyRIPK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) antibodyKO Validated RIPK2 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. McCarthy, J. V., Ni, J., Dixit, V. M. RIP2 is a novel NF-kappa-B-activating and cell death-inducing kinase. J. Biol. Chem. 273: 16968-16975, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))
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别名
- RIPK2
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背景
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Synonyms: Fibrinogen alpha chain, FGA
Tissue Specificity: Detected in blood plasma (at protein level).
Background: RIPK2(Receptor-interacting serine/threonine-protein kinase 2), also known as CARD3, CARDIAK, RICK, RIP2, is anenzymethat in humans is encoded by theRIPK2gene.It has 540-amino acid protein in length.Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway. This gene encodes a member of the receptor-interacting protein(RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminalcaspase recruitment domain(CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator ofNF-kappa Band inducer of apoptosis in response to various stimuli, CARDIAK(CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit.
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分子量
- 61 kDa
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基因ID
- 8767
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UniProt
- O43353
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途径
- TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades
抗原
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