ADRM1 抗体 (AA 15-390)
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北京 101111
Quick Overview for ADRM1 抗体 (AA 15-390) (ABIN7600108)
抗原
See all ADRM1 (Adrm1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-390
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原理
- Anti-ADRM1/ARM-1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-ADRM1/ARM-1 Antibody (ABIN7600108). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ADRM1/ARM-1 recombinant protein (Position: S15-K390).
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亚型
- IgG
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anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 18-407) antibody
Adrm1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 108-407) antibodyAdrm1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 2-407) antibodyAdrm1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (Internal Region) antibodyAdrm1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 368-397), (C-Term) antibodyAdrm1 适用: 人 WB 宿主: 兔 Polyclonal RB41862 unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 18-407) antibodyAdrm1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) antibodyAdrm1 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (C-Term) antibodyAdrm1 适用: 人, 小鼠, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (C-Term) antibodyAdrm1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adhesion Regulating Molecule 1 (Adrm1) (AA 357-407) antibodyAdrm1 适用: 人, 小鼠 WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
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别名
- ADRM1
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背景
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Synonyms: Ran-specific GTPase-activating protein,Ran-binding protein 1,RanBP1,RANBP1,
Tissue Specificity: Ubiquitously expressed. Present at highest levels in the brain, at high levels in the placenta and testis, at intermediate levels in the intestine, ovary, skeletal muscle and thymus and at lower levels in heart, kidney, liver, lung, pancreas, prostate and spleen. In the kidney, it is widely expressed in tubules, but sparsely expressed in the glomerulus (PubMed:24676636). Expression is significantly increased in renal biopsy specimens from idiopathic FSGS (PubMed:24676636). Overexpressed in many tumor types including breast, colorectal, endometrial, hepatic, kidney, lung, ovarian and pancreatic tumors.
Background: Proteasomal ubiquitin receptor ADRM1 is a protein that in humans is encoded by the ADRM1 gene. This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an in effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.
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分子量
- 42 kDa
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基因ID
- 11047
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UniProt
- Q16186
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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