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Peroxiredoxin 6 抗体 (AA 15-224)

This anti-Peroxiredoxin 6 antibody is a 小鼠 单克隆 antibody detecting Peroxiredoxin 6 in WB, IHC, ICC, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7600102
发货至: 中国

Quick Overview for Peroxiredoxin 6 抗体 (AA 15-224) (ABIN7600102)

抗原

See all Peroxiredoxin 6 (PRDX6) 抗体
Peroxiredoxin 6 (PRDX6)

适用

  • 82
  • 43
  • 39
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 85
  • 10
  • 2
小鼠

克隆类型

  • 75
  • 20
单克隆

标记

  • 56
  • 12
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
This Peroxiredoxin 6 antibody is un-conjugated

应用范围

  • 73
  • 47
  • 29
  • 25
  • 23
  • 14
  • 13
  • 6
  • 4
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

6I8
  • 抗原表位

    • 18
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-224

    原理

    Anti-PRDX6 Antibody Picoband® (monoclonal, 6I8)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PRDX6 Antibody Picoband® (monoclonal, 6I8) (ABIN7600102). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Peroxiredoxin 6 recombinant protein (Position: E15-P224). Human Peroxiredoxin 6 shares 90% and 91% amino acid (aa) sequence identity with mouse and rat Peroxiredoxin 6, respectively.

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Ambruso DR, et al. Peroxiredoxin 6 translocates to the plasma membrane during neutrophil activation and is required for optimal NADPH oxidase activity. Biochim Biophys Acta, 2012 Feb. 2. Chhunchha B, et al. Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription. FEBS J, 2014 Aug. 3. Guo HW, et al. Expression of peroxiredoxin 6 in gastric cancer and its clinical significance. Zhonghua Yi Xue Za Zhi, 2012 Sep 11.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Peroxiredoxin 6 (PRDX6)

    别名

    PRDX6

    背景

    Synonyms: Peroxiredoxin-6,1.11.1.15,1-Cys peroxiredoxin,1-Cys PRX,24 kDa protein,Acidic calcium-independent phospholipase A2,aiPLA2,3.1.1.-,Antioxidant protein 2,Liver 2D page spot 40,Non-selenium glutathione peroxidase,NSGPx,1.11.1.9,Red blood cells page spot 12,PRDX6,AOP2, KIAA0106,

    Tissue Specificity: Widely expressed in fetal and adult tissues.

    Background: PRDX6 is also known as PRX, p29 or AOP2. The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell, it can reduce H (2)O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

    分子量

    29 kDa.

    基因ID

    9588

    UniProt

    P30041
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