Transgelin 抗体 (AA 15-170)
Quick Overview for Transgelin 抗体 (AA 15-170) (ABIN7600099)
抗原
See all Transgelin (TAGLN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-170
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原理
- Anti-TAGLN/Transgelin Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TAGLN/Transgelin Antibody Picoband® (ABIN7600099). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human TAGLN/Transgelin recombinant protein (Position: Q15-E170).
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亚型
- IgG
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anti-Transgelin (TAGLN) (C-Term) antibody
Verified TAGLN 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyTAGLN 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) antibodyKO Validated TAGLN 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated
anti-Transgelin (TAGLN) (AA 2-201) antibodyTAGLN 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transgelin (TAGLN) (AA 19-112) antibodyTAGLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Transgelin (TAGLN) (AA 1-201) antibodyTAGLN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Transgelin (TAGLN) (AA 24-51), (N-Term) antibodyTAGLN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19881 unconjugated
anti-Transgelin (TAGLN) (C-Term) antibodyTAGLN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: TAGLN transgelin". 2. Kobayashi R, Kubota T, Hidaka H (Mar 1994). "Purification, characterization, and partial sequence analysis of a new 25- kDa actin-binding protein from bovine aorta: a SM22 homolog". Biochem Biophys Res Commun. 198 (3): 1275-80. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Transgelin (TAGLN)
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别名
- TAGLN
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背景
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Synonyms: Sodium-dependent phosphate transport protein 2B, Sodium-phosphate transport protein 2B, Na (+)-dependent phosphate cotransporter 2B, NaPi3b, Sodium/phosphate cotransporter 2B, Na (+)/Pi cotransporter 2B, NaPi-2b, Solute carrier family 34 member 2, SLC34A2
Tissue Specificity: Highly expressed in lung. Also detected in pancreas, kidney, small intestine, ovary, testis, prostate and mammary gland. In lung, it is found in alveolar type II cells but not in bronchiolar epithelium.
Background: Transgelin, also known as SM22 alpha, is a protein that in humans is encoded by the TAGLN gene. This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.
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分子量
- 22 kDa
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基因ID
- 6876
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UniProt
- Q01995
抗原
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