NK2 Homeobox 5 抗体 (AA 15-132)
Quick Overview for NK2 Homeobox 5 抗体 (AA 15-132) (ABIN7600098)
抗原
See all NK2 Homeobox 5 (NKX2-5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-132
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原理
- Anti-Nkx2.5/NKX2-5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Nkx2.5/NKX2-5 Antibody Picoband® (ABIN7600098). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Nkx2.5/NKX2-5 recombinant protein (Position: K15-R132).
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亚型
- IgG
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anti-NK2 Homeobox 5 (NKX2-5) (Internal Region) antibody
Verified NKX2-5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-324) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4-G5 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 98-133) antibodyNKX2-5 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB52360 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 192-225) antibodyNKX2-5 适用: 小鼠, 大鼠, Hamster WB 宿主: 兔 Polyclonal RB51144 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 1-130) antibodyNKX2-5 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-NK2 Homeobox 5 (NKX2-5) (AA 300-324) antibodyNKX2-5 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NK2 Homeobox 5 (NKX2-5) antibodyNKX2-5 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E1 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hiroi, Y., Kudoh, S., Monzen, K., Ikeda, Y., Yazaki, Y., Nagai, R., Komuro, I. Tbx5 associates withNkx2-5 and synergistically promotes cardiomyocyte differentiation. Nature Genet. 28: 276-280, 2001. 2. Shiojima, I., Komuro, I., Inazawa, J., Nakahori, Y., Matsushita, I., Abe, T., Nagai, R., Yazaki, Y.Assignment of cardiac homeobox gene CSX to human chromosome 5q34. Genomics 27: 204-206, 1995. 3. Turbay D, Wechsler SB, Blanchard KM, Izumo S (January 1997). "Molecular cloning, chromosomal mapping, and characterization of the human cardiac-specific homeobox gene hCsx". Mol Med 2 (1): 86-96. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NK2 Homeobox 5 (NKX2-5)
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别名
- NKX2-5
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背景
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Synonyms: Interstitial collagenase, Fibroblast collagenase, Matrix metalloproteinase-1, MMP-1, 22 kDa interstitial collagenase, 27 kDa interstitial collagenase, MMP1, CLG
Background: Homeobox protein Nkx-2.5, also known as NKX2E or CSX is a protein that in humans is encoded by the NKX2-5 gene. It is mapped to 5q35.1. Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development. Nkx2.5 and Tbx5 ly bound to the promoter of the gene encoding cardiac-specific natriuretic peptide precursor type A (NPPA) in tandem, and both transcription factors showed synergistic activation. The cardiac homeobox protein Nkx2.5 is essential in cardiac development, and mutations in CSX (which encodes Nkx2.5) cause various congenital heart malformations.
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分子量
- 35 kDa
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基因ID
- 1482
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UniProt
- P52952
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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