PNPLA6 抗体 (AA 15-1296)
Quick Overview for PNPLA6 抗体 (AA 15-1296) (ABIN7600097)
抗原
See all PNPLA6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 15-1296
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原理
- Anti-PNPLA6 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PNPLA6 Antibody Picoband® (ABIN7600097). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PNPLA6 recombinant protein (Position: H15-E1296).
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亚型
- IgG
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anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (Internal Region) antibody
PNPLA6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (AA 1229-1327) antibodyPNPLA6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (AA 345-493) antibodyPNPLA6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (N-Term) antibodyPNPLA6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (Internal Region) antibodyPNPLA6 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (C-Term) antibodyPNPLA6 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (C-Term) antibodyPNPLA6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (AA 965-1137) antibodyPNPLA6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Patatin-Like phospholipase Domain Containing 6 (PNPLA6) (Internal Region) antibodyPNPLA6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bargal, R., Avidan, N., Ben-Asher, E., Olender, Z., Zeigler, M., Frumkin, A., Raas-Rothschild, A., Glusman, G., Lancet, D., Bach, G. Identification of the gene causing mucolipidosis type IV. Nature Genet. 26: 118-123, 2000. 2. Chalvon-Demersay, A., Tardieu, M., Crosnier, H., Benichou, J. J., Pienkowski, C., Rochiccioli, P., Labrune, B. Syndrome de Laurence-Moon (Bardet-Biedl) avec deficit en hormone de croissance. Arch. Franc. Pediat. 50: 859-862, 1993. 3. Hufnagel, R. B., Arno, G., Hein, N. D., Hersheson, J., Prasad, M., Anderson, Y., Krueger, L. A., Gregory, L. C., Stoetzel, C., Jaworek, T. J., Hull, S., Li, A., and 20 others. Neuropathy target esterase impairments cause Oliver-McFarlane and Laurence-Moon syndromes. J. Med. Genet. 52: 85-94, 2015. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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别名
- PNPLA6
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背景
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Synonyms: Carbonic anhydrase 12, Carbonate dehydratase XII, Carbonic anhydrase XII, CA-XII, Tumor antigen HOM-RCC-3.1.3, CA12
Tissue Specificity: Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium (PubMed:26911677).
Background: Neuropathy target esterase, also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded by the PNPLA6 gene. This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 150 kDa
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基因ID
- 10908
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途径
- Ribonucleoside Biosynthetic Process
抗原
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