Cadherin 13 抗体 (AA 149-692)
Quick Overview for Cadherin 13 抗体 (AA 149-692) (ABIN7600095)
抗原
See all Cadherin 13 (CDH13) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 149-692
-
原理
- Anti-H Cadherin/CDH13 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-H Cadherin/CDH13 Antibody Picoband® (ABIN7600095). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human H Cadherin/CDH13 recombinant protein (Position: E149-A692).
-
亚型
- IgG
-
-
anti-Cadherin 13 (CDH13) antibody
CDH13 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 23-133) antibodyCDH13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 1-713) antibodyCDH13 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (Internal Region) antibodyCDH13 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 301-400) antibodyCDH13 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 1-713) antibodyCDH13 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 179-366) antibodyCDH13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 478-690) antibodyCDH13 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 589-617), (C-Term) antibodyCDH13 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 13 (CDH13) (AA 146-174), (N-Term) antibodyCDH13 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kremmidiotis, G., Baker, E., Crawford, J., Eyre, H. J., Nahmias, J., Callen, D. F. Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Genomics 49: 467-471, 1998. 2. Lee, S. W. H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nature Med. 2: 776-782, 1996. 3. Sato, M., Mori, Y., Sakurada, A., Fujimura, S., Horii, A. The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum. Genet. 103: 96-101, 1998. Note: Erratum: Hum. Genet. 103: 532 only, 1998. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Cadherin 13 (CDH13)
-
别名
- CDH13
-
背景
-
Synonyms: Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Background: T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
-
分子量
- 105 kDa, 130 kDa
-
基因ID
- 1012
-
UniProt
- P55290
-
途径
- EGFR Signaling Pathway, Cell-Cell Junction Organization
抗原
-
