FXR1 抗体 (AA 149-614)
Quick Overview for FXR1 抗体 (AA 149-614) (ABIN7600093)
抗原
See all FXR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 149-614
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原理
- Anti-FXR1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-FXR1 Antibody Picoband® (ABIN7600093). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FXR1 recombinant protein (Position: D149-A614).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bolivar, J., Guelman, S., Iglesias, C., Ortiz, M., Valdivia, M. M. The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. J. Biol. Chem. 273: 17122-17127, 1998. 2. Coy, J. F., Sedlacek, Z., Bachner, D., Hameister, H., Joos, S., Lichter, P., Delius, H., Poustka, A. Highly conserved 3-prime UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum. Molec. Genet. 4: 2209-2218, 1995. 3. Darnell, J. C., Fraser, C. E., Mostovetsky, O., Darnell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))
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别名
- FXR1
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背景
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Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,
Tissue Specificity: Testis and brain.
Background: Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene. The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 80 kDa
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基因ID
- 8087
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UniProt
- P51114
抗原
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