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FXR1 抗体 (AA 149-614)

This anti-FXR1 antibody is a 兔 多克隆 antibody detecting FXR1 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7600093
发货至: 中国

Quick Overview for FXR1 抗体 (AA 149-614) (ABIN7600093)

抗原

See all FXR1 抗体
FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 57
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克隆类型

  • 54
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多克隆

标记

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This FXR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 9
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    AA 149-614

    原理

    Anti-FXR1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-FXR1 Antibody Picoband® (ABIN7600093). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FXR1 recombinant protein (Position: D149-A614).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bolivar, J., Guelman, S., Iglesias, C., Ortiz, M., Valdivia, M. M. The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. J. Biol. Chem. 273: 17122-17127, 1998. 2. Coy, J. F., Sedlacek, Z., Bachner, D., Hameister, H., Joos, S., Lichter, P., Delius, H., Poustka, A. Highly conserved 3-prime UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum. Molec. Genet. 4: 2209-2218, 1995. 3. Darnell, J. C., Fraser, C. E., Mostovetsky, O., Darnell, R. B. Discrimination of common and unique RNA-binding activities among fragile X mental retardation protein paralogs. Hum. Molec. Genet. 18: 3164-3177, 2009.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    FXR1 (Fragile X Mental Retardation, Autosomal Homolog 1 (FXR1))

    别名

    FXR1

    背景

    Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

    Tissue Specificity: Testis and brain.

    Background: Fragile X mental retardation syndrome-related protein 1 is a protein that in humans is encoded by the FXR1 gene. The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.

    分子量

    80 kDa

    基因ID

    8087

    UniProt

    P51114
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