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CD13 抗体 (AA 148-966)

This anti-CD13 antibody is a 小鼠 单克隆 antibody detecting CD13 in WB 和 IHC. Suitable for 人, 大鼠 和 猴.
产品编号 ABIN7600090
发货至: 中国

Quick Overview for CD13 抗体 (AA 148-966) (ABIN7600090)

抗原

See all CD13 (ANPEP) 抗体
CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

适用

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人, 大鼠, 猴

宿主

  • 106
  • 63
  • 15
  • 1
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  • 1
小鼠

克隆类型

  • 128
  • 54
  • 1
单克隆

标记

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This CD13 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)

克隆位点

5B9
  • 抗原表位

    • 16
    • 7
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    • 1
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    AA 148-966

    原理

    Anti-CD13/ANPEP Picoband® Antibody (monoclonal, 5B9)

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CD13/ANPEP Picoband® Antibody (monoclonal, 5B9) (ABIN7600090). Tested in IHC, WB applications. This antibody reacts with Human, Monkey, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CD13/ANPEP recombinant protein (Position: D148-S966).

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Rat, Monkey
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
    1. Delmas, B., Gelfi, J., L'Haridon, R., Vogel, L. K., Sjostrom, H., Noren, O., Laude, H. Aminopeptidase N is a major receptor for the enteropathogenic coronavirus TGEV. Nature 357: 417-420, 1992. 2. Kruse, T. A., Bolund, L., Grzeschik, K.-H., Ropers, H. H., Olsen, J., Sjostrom, H., Noren, O. Assignment of the human aminopeptidase N (peptidase E) gene to chromosome 15q13-qter. FEBS Lett. 239: 305-308, 1988. 3. Look, A. T., Ashmun, R. A., Shapiro, L. H., Peiper, S. C. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83: 1299-1307, 1989.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

    别名

    ANPEP

    背景

    Synonyms: Arylsulfatase A, ASA, Cerebroside-sulfatase, Arylsulfatase A component B, Arylsulfatase A component C, ARSA

    Background: Membrane alanyl aminopeptidase (EC 3.4.11.2) also known as alanyl aminopeptidase (AAP) or aminopeptidase N (AP-N) is an enzyme that in humans is encoded by the ANPEP gene. It is mapped to 15q26.1. Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

    分子量

    150 kDa

    基因ID

    290

    UniProt

    P15144

    途径

    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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