Espin 抗体 (AA 143-854)
Quick Overview for Espin 抗体 (AA 143-854) (ABIN7600060)
抗原
See all Espin (ESPN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 143-854
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原理
- Anti-ESPN Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-ESPN Antibody Picoband® (ABIN7600060). Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human ESPN recombinant protein (Position: H143-Y854). Human ESPN shares 75.6% and 78.1% amino acid (aa) sequence identity with mouse and rat ESPN, respectively.
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亚型
- IgG
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anti-Espin (ESPN) (AA 17-45), (N-Term) antibody
ESPN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20951 unconjugated
anti-Espin (ESPN) (AA 585-854) antibodyESPN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Espin (ESPN) antibodyESPN 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. Ahmed, Z. M., Jaworek, T., Sarangdhar, G. N., Zheng, L., Gul, K., Khan, S. N., Friedman, T. B., Sisk, R. A., Bartles, J. R., Riazuddin, S., Riazuddin, S. Inframe deletion of human ESPN is associated with deafness, vestibulopathy and vision impairment. J. Med. Genet. 55: 479-488, 2018. 2. Bartles, J. R., Wierda, A., Zheng, L. Identification and characterization of espin, an actin-binding protein localized to the F-actin-rich junctional plaques of Sertoli cell ectoplasmic specializations. J. Cell Sci. 109: 1229-1239, 1996. 3. Bartles, J. R., Zheng, L., Li, A., Wierda, A., Chen, B. Small espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli. J. Cell Biol. 143: 107-119, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Espin (ESPN)
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别名
- ESPN
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背景
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Synonyms: ESPN, DFNB36, LP2654, Espin, Autosomal recessive deafness type 36 protein, Ectoplasmic specialization protein
Background: This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
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分子量
- 110 kDa
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基因ID
- 83715
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途径
- Sensory Perception of Sound
抗原
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