MEIOB 抗体 (AA 140-442)
Quick Overview for MEIOB 抗体 (AA 140-442) (ABIN7600042)
抗原
See all MEIOB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-442
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原理
- Anti-MEIOB Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MEIOB Antibody Picoband® (ABIN7600042). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MEIOB recombinant protein (Position: I140-V442). Human MEIOB shares 77.9% and 76.1% amino acid (aa) sequence identity with mouse and rat MEIOB, respectively.
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亚型
- IgG
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anti-Meiosis Specific with OB Domains (MEIOB) (C-Term) antibody
MEIOB 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Meiosis Specific with OB Domains (MEIOB) (Middle Region) antibodyMEIOB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Meiosis Specific with OB Domains (MEIOB) (C-Term) antibodyMEIOB 适用: 人, 小鼠, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Meiosis Specific with OB Domains (MEIOB) (Middle Region) antibodyMEIOB 适用: 人, 小鼠, 犬, 马, 兔, 大鼠, 豚鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, Human
1. Caburet, S., Todeschini, A.-L., Petrillo, C., Martini, E., Farran, N. D., Legois, B., Livera, G., Younis, J. S., Shalev, S., Veitia, R. A. A truncating MEIOB mutation responsible for familial primary ovarian insufficiency abolishes its interaction with its partner SPATA22 and their recruitment to DNA double-strand breaks. EBioMedicine 42: 524-531, 2019. 2. Gershoni, M., Hauser, R., Yogev, L., Lehavi, O., Azem, F., Yavetz, H., Pietrokovski, S., Kleiman, S. E. A familial study of azoospermic men identifies three novel causative mutations in three new human azoospermia genes. Genet. Med. 19: 998-1006, 2017. 3. Luo, M., Yang, F., Leu, N. A., Landaiche, J., Handel, M. A., Benavente, R., La Salle, S., Wang, P. J. MEIOB exhibits single-stranded DNA-binding and exonuclease activities and is essential for meiotic recombination. Nature Commun. 4: 2788, 2013. Note: Electronic Article. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MEIOB (Meiosis Specific with OB Domains (MEIOB))
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别名
- MEIOB
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背景
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Synonyms: MEIOB, C16orf73, Meiosis-specific with OB domain-containing protein, EC 3.1.-.-
Background: Predicted to enable chromatin binding activity, single-stranded DNA 3'-5' exodeoxyribonuclease activity, and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination, fertilization, and meiotic nuclear division. Predicted to be located in cytoplasm. Implicated in spermatogenic failure 22.
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分子量
- 49 kDa
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基因ID
- 254528
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UniProt
- Q8N635
抗原
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