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RCC1 抗体 (AA 14-421)

This anti-RCC1 antibody is a 小鼠单克隆 antibody detecting RCC1 in WB. Suitable for 人.

产品编号 ABIN7600023

发货至: 中国

Quick Overview for RCC1 抗体 (AA 14-421) (ABIN7600023)

抗原

See all RCC1 抗体

RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

适用

72
17
16
6
6
6
6
5
4
3
2
2
1
1

人

宿主

小鼠

克隆类型

单克隆

标记

38
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1

This RCC1 antibody is un-conjugated

应用范围

48
26
26
16
14
11
10
8
7
6
2
1

Western Blotting (WB)

克隆位点

7B5D2

Discover our top product RCC1 Primary Antibody

抗原表位
15

15

4

3

2

2

2

2

2

2

2

1

1

1

1

1
AA 14-421

原理

Anti-RCC1 Antibody Picoband® (monoclonal, 7B5D2)

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-RCC1 Antibody Picoband® (monoclonal, 7B5D2) (ABIN7600023). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human RCC1 recombinant protein (Position: A14-S421).

亚型

IgG1
anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-240) antibody
RCC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) antibody
RCC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 312-421) antibody
RCC1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F1 unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 312-421) antibody
RCC1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 1C1 unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) antibody
RCC1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) antibody
RCC1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 301-350) antibody
RCC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) (AA 1-421) antibody
RCC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) antibody
RCC1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Regulator of Chromosome Condensation 1 (RCC1) antibody
RCC1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 332CT2-1-1 unconjugated

应用备注

Western blot, 0.25-0.5 μg/mL, Human
1. Bischoff, F. R., Maier, G., Tilz, G., Ponstingl, H. A 47- kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation. Proc. Nat. Acad. Sci. 87: 8617-8621, 1990. 2. Carazo-Salas, R. E., Guarguaglini, G., Gruss, O. J., Segref, A., Karsenti, E., Mattaj, I. W. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400: 178-181, 1999. 3. Chen, T., Muratore, T. L., Schaner-Tooley, C. E., Shabanowitz, J., Hunt, D. F., Macara, I. G. N-terminal alpha-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nature Cell Biol. 9: 596-603, 2007.

限制

仅限研究用
状态

Lyophilized

溶解方式

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
抗原

RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

别名

RCC1

背景

Synonyms: Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48
Background: CHC1, also named as RCC1, SNHG3-RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. The geneID has updated as 1104 recently.

分子量

47 kDa

基因ID

1104

UniProt

P18754

途径

Chromatin Binding, Protein targeting to Nucleus

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