PRDM8 抗体 (AA 14-405)
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- 抗原 See all PRDM8 抗体
- PRDM8 (PR Domain Containing 8 (PRDM8))
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抗原表位
- AA 14-405
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM8 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 原理
- Anti-PRDM8 Antibody Picoband®
- 交叉反应 (详细)
- No cross-reactivity with other proteins.
- 产品特性
- Anti-PRDM8 Antibody Picoband® (ABIN7600021). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human PRDM8 recombinant protein (Position: D14-D405).
- 亚型
- IgG
- Top Product
- Discover our top product PRDM8 Primary Antibody
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- 应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Eom, G. H., Kim, K., Kim, S.-M., Kee, H. J., Kim, J.-Y., Jin, H. M., Kim, J.-R., Kim, J. H., Choe, N., Kim, K.-B., Lee, J., Kook, H., Kim, N., Seo, S.-B. Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis. Biochem. Biophys. Res. Commun. 388: 131-136, 2009. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/11/2015. 3. Komai, T., Iwanari, H., Mochizuki, Y., Hamakubo, T., Shinkai, Y. Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr. Patterns 9: 503-514, 2009. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- 抗原
- PRDM8 (PR Domain Containing 8 (PRDM8))
- 别名
- PRDM8 (PRDM8 产品)
- 背景
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Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7
Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
Background: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.
- 分子量
- 70 kDa
- 基因ID
- 56978
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