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SIRT6 抗体 (AA 14-355)

This anti-SIRT6 antibody is a 兔 多克隆 antibody detecting SIRT6 in WB, ELISA, ICC, IF 和 FACS. Suitable for 人.
产品编号 ABIN7600019
发货至: 中国

Quick Overview for SIRT6 抗体 (AA 14-355) (ABIN7600019)

抗原

See all SIRT6 抗体
SIRT6 (Sirtuin 6 (SIRT6))

适用

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宿主

  • 84
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克隆类型

  • 79
  • 20
多克隆

标记

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  • 1
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This SIRT6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 12
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
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    • 1
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    AA 14-355

    原理

    Anti-SIRT6 Antibody Picoband®

    产品特性

    Anti-SIRT6 Antibody Picoband® (ABIN7600019). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human SIRT6 recombinant protein (Position: D14-S355). Human SIRT6 shares 82.7% amino acid (aa) sequence identity with both mouse SIRT6.
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Butzow, R., Huhtala, M.-L., Bohn, H., Virtanen, I., Seppala, M. Purification and characterization of placental protein 5. Biochem. Biophys. Res. Commun. 150: 483-490, 1988. Note: Erratum: Biochem. Biophys. Res. Commun. 151: 630-631, 1988. 2. Kisiel, W., Sprecher, C. A., Foster, D. C. Evidence that a second human tissue factor pathway inhibitor (TFPI-2) and human placental protein 5 are equivalent. (Letter) Blood 84: 4384-4385, 1994. 3. Ma, S., Chan, Y. P., Kwan, P. S., Lee, T. K., Yan, M., Tang, K. H., Ling, M. T., Vielkind, J. R., Guan, X.-Y., Chan, K. W. MicroRNA-616 induces androgen-independent growth of prostate cancer cells by suppressing expression of tissue factor pathway inhibitor TFPI-2. Cancer Res. 71: 583-592, 2011.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    SIRT6 (Sirtuin 6 (SIRT6))

    别名

    SIRT6

    背景

    Sirtuin 6 (SIRT6 or Sirt6) is a stress responsive protein deacetylase and mono-ADP ribosyltransferase enzyme encoded by the SIRT6 gene. This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    45 kDa

    基因ID

    51548

    UniProt

    Q8N6T7
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