CBR1 抗体 (AA 14-262)
Quick Overview for CBR1 抗体 (AA 14-262) (ABIN7600015)
抗原
See all CBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-262
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原理
- Anti-CBR1 Picoband® Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CBR1 Picoband® Antibody (ABIN7600015). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CBR1 recombinant protein (Position: N14-E262).
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Avramopoulos, D., Cox, T., Forrest, G. L., Chakravarti, A., Antonarakis, S. E. Linkage mapping of the carbonyl reductase (CBR) gene on human chromosome 21 using a DNA polymorphism in the 3-prime untranslated region. Genomics 13: 447-448, 1992. 2. Forrest, G. L., Akman, S., Krutzik, S., Paxton, R. J., Sparkes, R. S., Doroshow, J., Felsted, R. L., Glover, C. J., Mohandas, T., Bachur, N. R. Induction of a human carbonyl reductase gene located on chromosome 21. Biochim. Biophys. Acta 1048: 149-155, 1990. 3. Lemieux, N., Malfoy, B., Forrest, G. L. Human carbonyl reductase (CBR) localized to band 21q22.1 by high-resolution fluorescence in situ hybridization displays gene dosage effects in trisomy 21 cells. Genomics 15: 169-172, 1993. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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别名
- CBR1
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背景
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Synonyms: Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP (+)], NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E (2) 9-reductase, Short chain dehydrogenase/reductase family 21C member 1, CBR1, CBR, CRN, SDR21C1
Tissue Specificity: Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Background: Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene. It is mapped to 21q22.12. The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.
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分子量
- 36 kDa
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基因ID
- 873
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UniProt
- P16152
抗原
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