SHANK3 抗体 (AA 1391-1698)
Quick Overview for SHANK3 抗体 (AA 1391-1698) (ABIN7600006)
抗原
See all SHANK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1391-1698
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原理
- Anti-SHANK3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SHANK3 Antibody Picoband® (ABIN7600006). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SHANK3 recombinant protein (Position: E1391-H1698).
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亚型
- IgG
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anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (HRP)
SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 HRP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (FITC)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 FITC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Biotin)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 Biotin
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PE)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 PE
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (PerCP)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 PerCP
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (APC)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 APC
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 488)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 Atto 488
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 594)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 Atto 594
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibody (Atto 390)SHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 Atto 390
anti-SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3) (AA 840-857) antibodySHANK3 适用: 大鼠 WB, IHC, IP, ICC, IF, AA 宿主: 小鼠 Monoclonal S69 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: SHANK3 SH3 and multiple ankyrin repeat domains 3". 2. Boeckers TM, Bockmann J, Kreutz MR, Gundelfinger ED (2002). "ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic absorbance with an emerging role in human neurological disease".J. Neurochem. 81 (5): 903-10. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SHANK3 (SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3))
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别名
- SHANK3
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背景
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Synonyms: Histone deacetylase 5, HD5, Antigen NY-CO-9, HDAC5, KIAA0600
Tissue Specificity: Ubiquitous.
Background: SH3 and multiple ankyrin repeat domains 3 (Shank3), also known as proline-rich synapse-associated protein 2 (ProSAP2), is a protein that in humans is encoded by the SHANK3 gene. This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Additionally, Shank proteins play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified.
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分子量
- 180-190 kDa
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基因ID
- 85358
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途径
- Synaptic Membrane, Tube Formation, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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