CENPE 抗体 (AA 1390-2474)
Quick Overview for CENPE 抗体 (AA 1390-2474) (ABIN7600005)
抗原
See all CENPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1390-2474
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原理
- Anti-Cenpe Antibody Picoband®
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产品特性
- Anti-Cenpe Antibody Picoband® (ABIN7600005). Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived mouse Cenpe recombinant protein (Position: Q1390-Q2474). Mouse Cenpe shares 49.9% amino acid (aa) sequence identity with human Cenpe, respectively.
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anti-Centromere Protein E, 312kDa (CENPE) antibody
CENPE 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) antibodyCENPE 适用: 人 IP, ICC, IF, FACS 宿主: 小鼠 Monoclonal 1H12 unconjugated
anti-Centromere Protein E, 312kDa (CENPE) antibodyCENPE 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) (AA 2450-2590) antibodyCENPE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) (C-Term) antibodyCENPE 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) (C-Term) antibodyCENPE 适用: 人 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) (AA 2542-2701) antibodyCENPE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Centromere Protein E, 312kDa (CENPE) (AA 2222-2361) antibodyCENPE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Abrieu, A., Kahana, J. A., Wood, K. W., Cleveland, D. W. CENP-E as an essential component of the mitotic checkpoint in vitro. Cell 102: 817-826, 2000. 2. Barisic, M., Silva e Sousa, R., Tripathy, S. K., Magiera, M. M., Zaytsev, A. V., Pereira, A. L., Janke, C., Grishchuk, E. L., Maiato, H. Microtubule detyrosination guides chromosomes during mitosis. Science 348: 799-803, 2015. 3. Gross, M. B. Personal Communication. Baltimore, Md. 11/4/2014. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- CENPE (Centromere Protein E, 312kDa (CENPE))
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别名
- Cenpe
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背景
- Centromere-associated protein E is a protein that in humans is encoded by the CENPE gene. Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.
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分子量
- 300 kDa
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基因ID
- 229841
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途径
- M Phase, Maintenance of Protein Location
抗原
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