FGA 抗体 (AA 139-784)
Quick Overview for FGA 抗体 (AA 139-784) (ABIN7600004)
抗原
See all FGA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 139-784
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原理
 - Anti-Fibrinogen alpha chain/FGA Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-Fibrinogen alpha chain/FGA Antibody Picoband® (ABIN7600004). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human Fibrinogen alpha chain/FGA recombinant protein (Position: E139-Q784).
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahn, H. J., Glickman, J. F., Poon, K. L., Zamolodchikov, D., Jno-Charles, O. C., Norris, E. H., Strickland, S. A novel A-beta-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice. J. Exp. Med. 211: 1049-1062, 2014. 2. Akassoglou, K., Yu, W.-M., Akpinar, P., Strickland, S. Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation. Neuron 33: 861-875, 2002. 3. Alving, B. M., Henschen, A. H. Fibrinogen Giessen I: a congenital homozygously expressed dysfibrinogenemia with A-alpha arg-to-his substitution. Am. J. Hemat. 25: 479-482, 1987. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. 
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- FGA (Fibrinogen alpha Chain (FGA))
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别名
 - FGA
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背景
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Synonyms: Fibrinogen alpha chain, FGA
Tissue Specificity: Detected in blood plasma (at protein level).
Background: Fibrinogen alpha chain?is a?protein?that in humans is encoded by the?FGA?gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.
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分子量
 - 95 kDa
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基因ID
 - 2243
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UniProt
 - P02671
 
抗原
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