PDLIM4 抗体 (AA 137-271)
Quick Overview for PDLIM4 抗体 (AA 137-271) (ABIN7599989)
抗原
See all PDLIM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 137-271
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原理
- Anti-PDLIM4 Antibody Picoband®
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产品特性
- Anti-PDLIM4 Antibody Picoband® (ABIN7599989). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDLIM4 recombinant protein (Position: Y137-D271). Human PDLIM4 shares 91.2% and 89% amino acid (aa) sequence identity with mouse and rat PDLIM4, respectively.
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anti-PDZ and LIM Domain 4 (PDLIM4) (C-Term) antibody
Verified PDLIM4 适用: 人 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PDZ and LIM Domain 4 (PDLIM4) antibodyPDLIM4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 4 (PDLIM4) (AA 81-243) antibodyPDLIM4 适用: 人 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-PDZ and LIM Domain 4 (PDLIM4) (AA 1-246) antibodyPDLIM4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PDZ and LIM Domain 4 (PDLIM4) (C-Term) antibodyPDLIM4 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bashirova, A. A., Markelov, M. L., Shlykova, T. V., Levshenkova, E. V., Alibaeva, R. A., Frolova, E. I. The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts. Gene 210: 239-245, 1998. 2. Boumber, Y. A., Kondo, Y., Chen, X., Shen, L., Gharibyan, V., Konishi, K., Estey, E., Kantarjian, H., Garcia-Manero, G., Issa, J.-P. J. RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. Cancer Res. 67: 1997-2005, 2007. 3. Kiess, M., Scharm, B., Aguzzi, A., Hajnal, A., Klemenz, R., Schwarte-Waldhoff, I., Schafer, R. Expression of ril, a novel LIM domain gene, is down-regulated in Hras-transformed cells and restored in phenotypic revertants. Oncogene 10: 61-68, 1995. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PDLIM4 (PDZ and LIM Domain 4 (PDLIM4))
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别名
- PDLIM4
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背景
- PDZ and LIM domain protein 4 is a protein that in humans is encoded by the PDLIM4 gene. RIL, also known as PDLIM4 is a putative tumor suppressor gene. RIL is transcriptionally repressed by hypermethylation in a variety of tumors including breast and prostate. The difference in methylation status of RIL between normal and cancerous tissues is being investigated as to determine the use of RIL as a potential biomarker. Two isoforms of human RIL one have been identified.
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分子量
- 35 kDa
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基因ID
- 8572
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UniProt
- P50479
抗原
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