Neurogenin 3 抗体 (AA 137-214)
Quick Overview for Neurogenin 3 抗体 (AA 137-214) (ABIN7599987)
抗原
See all Neurogenin 3 (NEUROG3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 137-214
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原理
- Anti-NEUROG3 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-NEUROG3 Antibody Picoband® (ABIN7599987). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NEUROG3 recombinant protein (Position: Q137-L214). Human NEUROG3 shares 72.2% amino acid (aa) sequence identity with mouse NEUROG3.
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亚型
- IgG
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Gradwohl, G., Dierich, A., LeMeur, M., Guillemot, F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Nat. Acad. Sci. 97: 1607-1611, 2000. 2. Kim, S.-H., Warram, J. H., Krolewski, A. S., Doria, A. Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes. J. Clin. Endocr. Metab. 86: 2320-2322, 2001. 3. Lee, C. S., Perreault, N., Brestelli, J. E., Kaestner, K. H. Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev. 16: 1488-1497, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Neurogenin 3 (NEUROG3)
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别名
- NEUROG3
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背景
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Synonyms: NEUROG3, ATOH5, BHLHA7, NGN3, Neurogenin-3, NGN-3, Class A basic helix-loop-helix protein 7, bHLHa7, Protein atonal homolog 5
Background: The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).
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分子量
- 23 kDa
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基因ID
- 50674
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UniProt
- Q9Y4Z2
抗原
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