HOMER1 抗体 (AA 135-354)
Quick Overview for HOMER1 抗体 (AA 135-354) (ABIN7599982)
抗原
See all HOMER1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-354
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原理
- Anti-HOMER1 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HOMER1 Antibody Picoband® (ABIN7599982). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human HOMER1 recombinant protein (Position: D135-S354).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -,
1. Ango, F., Prezeau, L., Muller, T., Tu, J. C., Xiao, B., Worley, P. F., Pin, J. P., Bockaert, J., Fagni, L. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer. Nature 411: 962-965, 2001. 2. Bangash, M. A., Park, J. M., Melnikova, T., Wang, D., Jeon, S. K., Lee, D., Syeda, S., Kim, J., Kouser, M., Schwartz, J., Cui, Y., Zhao, X., and 10 others. Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism. Cell 145: 758-772, 2011. Note: Retraction: Cell 152: 367 only, 2013. 3. Brakeman, P. R., Lanahan, A. A., O'Brien, R., Roche, K., Barnes, C. A., Huganir, R. L., Worley, P. F. Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386: 284-288, 1997. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HOMER1 (Homer Homolog 1 (HOMER1))
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别名
- HOMER1
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背景
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Synonyms: Transient receptor potential cation channel subfamily V member 3, TrpV3, Vanilloid receptor-like 3, VRL-3, TRPV3
Tissue Specificity: Abundantly expressed in CNS. Widely expressed at low levels. Detected in dorsal root ganglion. Expressed in the keratinocyte layers of the outer root sheath and, to lesser extent, to the matrix of the hair follicles.
Background: Homer protein homolog 1 or Homer1 is a neuronal protein that in humans is encoded by the HOMER1 gene. This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.
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分子量
- 50 kDa
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基因ID
- 9456
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途径
- Skeletal Muscle Fiber Development
抗原
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