TTDN1 抗体 (AA 135-179)
Quick Overview for TTDN1 抗体 (AA 135-179) (ABIN7599981)
抗原
See all TTDN1 (MPLKIP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-179
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原理
- Anti-MPLKIP Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MPLKIP Antibody Picoband® (ABIN7599981). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MPLKIP recombinant protein (Position: E135-C179). Human MPLKIP shares 97.7% amino acid (aa) sequence identity with mouse MPLKIP.
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亚型
- IgG
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anti-M-Phase Specific PLK1 Interacting Protein (MPLKIP) (Middle Region) antibody
MPLKIP 适用: 人, Cow, 犬, 豚鼠, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-M-Phase Specific PLK1 Interacting Protein (MPLKIP) (AA 151-177), (C-Term) antibodyMPLKIP 适用: 人 WB 宿主: 兔 Polyclonal RB37478 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL
1. Botta, E., Offman, J., Nardo, T., Ricotti, R., Zambruno, G., Sansone, D., Balestri, P., Raams, A., Kleijer, W. J., Jaspers, N. G. J., Sarasin, A., Lehmann, A. R., Stefanini, M. Mutations in the C7orf11 (TTDN1) gene in six nonphotosensitive trichothiodystrophy patients: no obvious genotype-phenotype relationships. Hum. Mutat. 28: 92-96, 2007. 2. Jackson, C. E., Weiss, L., Watson, J. H. L. 'Brittle' hair with short stature, intellectual impairment and decreased fertility: an autosomal recessive syndrome in an Amish kindred. Pediatrics 54: 201-212, 1974. 3. Nakabayashi, K., Amann, D., Ren, Y., Saarialho-Kere, U., Avidan, N., Gentles, S., MacDonald, J. R., Puffenberger, E. G., Christiano, A. M., Martinez-Mir, A., Salas-Alanis, J. C., Rizzo, R., Vamos, E., Raams, A., Les, C., Seboun, E., Jaspers, N. G. J., Beckmann, J. S., Jackson, C. E., Scherer, S. W. Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy. Am. J. Hum. Genet. 76: 510-516, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TTDN1 (MPLKIP) (M-Phase Specific PLK1 Interacting Protein (MPLKIP))
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别名
- MPLKIP
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背景
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Synonyms: MPLKIP, C7orf11, TTDN1, M-phase-specific PLK1-interacting protein, TTD non-photosensitive 1 protein
Background: The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy.
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分子量
- 19 kDa
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基因ID
- 136647
抗原
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