SENP6 抗体 (AA 135-1086)
Quick Overview for SENP6 抗体 (AA 135-1086) (ABIN7599979)
抗原
See all SENP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 135-1086
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原理
- Anti-SENP6 Picoband® Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SENP6 Picoband® Antibody (ABIN7599979). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SENP6 recombinant protein (Position: R135-K1086).
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亚型
- IgG
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anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-110) antibody
SENP6 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 4B7 unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (Internal Region) antibodyVerified SENP6 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1081-1112), (C-Term) antibodySENP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0664 unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) antibodySENP6 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term) antibodySENP6 适用: 人, Cow, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) antibodySENP6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-270) antibodySENP6 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (Internal Region) antibodySENP6 适用: 人, 小鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term) antibodySENP6 适用: 人, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 811-1112) antibodySENP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kim, K. I., Baek, S. H., Jeon, Y.-J., Nishimori, S., Suzuki, T., Uchida, S., Shimbara, N., Saitoh, H., Tanaka, K., Chung, C. H. A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. J. Biol. Chem. 275: 14102-14106, 2000. 2. Lima, C. D., Reverter, D. Structure of the human SENP7 catalytic domain and poly-SUMO deconjugation activities for SENP6 and SENP7. J. Biol. Chem. 283: 32045-32055, 2008. 3. Nagase, T., Ishikawa, K., Suyama, M., Kikuno, R., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 5: 277-286, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
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别名
- SENP6
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背景
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Synonyms: Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1, FKSG6
Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.
Background: Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene. It is mapped to 6q14.1. Ubiquitin-like molecules (UBLs), such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins. SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.
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分子量
- 150 kDa
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基因ID
- 26054
抗原
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