FHL1 抗体 (AA 133-179)
Quick Overview for FHL1 抗体 (AA 133-179) (ABIN7599973)
抗原
See all FHL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 133-179
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原理
- Anti-FHL1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FHL1 Antibody Picoband® (ABIN7599973). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FHL1 recombinant protein (Position: K133-Q179).
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亚型
- IgG
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anti-Four and A Half LIM Domains 1 (FHL1) (AA 23-120) antibody
FHL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) antibodyFHL1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (C-Term) antibodyFHL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (Internal Region) antibodyVerified FHL1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) antibodyFHL1 适用: 人, 大鼠, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 51-100) antibodyFHL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊, 兔, Pig, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 214-240), (C-Term) antibodyFHL1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19645 unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (N-Term) antibodyFHL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 绵羊, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 13-240) antibodyFHL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Four and A Half LIM Domains 1 (FHL1) (AA 1-280) antibodyFHL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Brown, S., McGrath, M. J., Ooms, L. M., Gurung, R., Maimone, M. M., Mitchell, C. A. Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1: localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes suggests distinct roles in the cytoskeleton and in nuclear-cytoplasmic communication. J. Biol. Chem. 274: 27083-27091, 1999. 2. Emmanuele, V., Kubota, A., Garcia-Diaz, B., Garone, C., Akman, H. O., Sanchez-Gutierrez, D., Escudero, L. M., Kariya, S., Homma, S., Tanji, K., Quinzii, C. M., Hirano, M. Fhl1 W122S causes loss of protein function and late-onset mild myopathy. Hum. Molec. Genet. 24: 714-726, 2015. 3. Fimia, G. M., De Cesare, D., Sassone-Corsi, P. A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM. Molec. Cell. Biol. 20: 8613-8622, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FHL1 (Four and A Half LIM Domains 1 (FHL1))
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别名
- FHL1
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背景
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Synonyms: Four and a half LIM domains protein 1, FHL-1, KyoT, RBP-associated molecule 14-1, RAM14-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1
Tissue Specificity: Isoform 1 seems to be most abundant in each tissue and isoform 2 much less abundant. Isoform 1 is highly expressed in skeletal muscle and lung, and to a lesser extent in heart, brain and kidney. Isoform 2 was found in brain, lung kidney and genital organs.
Background: Four and a half LIM domains protein 1 is a protein that in humans is encoded by the FHL1 gene. This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
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分子量
- 36 kDa
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基因ID
- 2273
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UniProt
- Q13642
抗原
-
