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MMP15 抗体 (AA 132-202)

This anti-MMP15 antibody is a 兔 多克隆 antibody detecting MMP15 in WB, ELISA, ICC, FACS 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599965
发货至: 中国

Quick Overview for MMP15 抗体 (AA 132-202) (ABIN7599965)

抗原

See all MMP15 抗体
MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MMP15 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 抗原表位

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    AA 132-202

    原理

    Anti-MT2-MMP/MMP15 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MT2-MMP/MMP15 Antibody Picoband® (ABIN7599965). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human MT2-MMP/MMP15 recombinant protein (Position: Y132-A202).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Mattei, M.-G., Roeckel, N., Olsen, B. R., Apte, S. S. Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively. Genomics 40: 168-169, 1997. 2. Sato, H., Tanaka, M., Takino, T., Inoue, M., Seiki, M. Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization. Genomics 39: 412-413, 1997. 3. Takino, T., Sato, H., Shinagawa, A., Seiki, M. Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs form a unique membrane-type subclass in the MMP family. J. Biol. Chem. 270: 23013-23020, 1995.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

    别名

    MMP15

    背景

    Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,

    Tissue Specificity: Mostly expressed in brain and liver.

    Background: Matrix metalloproteinase 15 also known as MMP15 is an enzyme that in humans is encoded by the MMP15 gene. This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression.

    分子量

    74 kDa

    基因ID

    4324

    UniProt

    P51511
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