FAM134B 抗体 (AA 131-446)
Quick Overview for FAM134B 抗体 (AA 131-446) (ABIN7599962)
抗原
See all FAM134B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-446
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原理
- Anti-RETREG1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RETREG1 Antibody Picoband® (ABIN7599962). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RETREG1 recombinant protein (Position: Q131-D446).
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亚型
- IgG
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anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 210-310) antibody
FAM134B 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 1-131) antibodyFAM134B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 160-209) antibodyFAM134B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (Middle Region) antibodyFAM134B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 1-356) antibodyFAM134B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 1-356) antibodyFAM134B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (AA 254-303) antibodyFAM134B 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 134, Member B (FAM134B) (Middle Region) antibodyFAM134B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ilgaz Aydinlar, E., Rolfs, A., Serteser, M., Parman, Y. Mutation in FAM134B causing hereditary sensory neuropathy with spasticity in a Turkish family. (Letter) Muscle Nerve 49: 774-775, 2014. 2. Khaminets, A., Heinrich, T., Mari, M., Grumati, P., Huebner, A. K., Akutsu, M., Liebmann, L., Stolz, A., Nietzsche, S., Koch, N., Mauthe, M., Katona, I., Qualmann, B., Weis, J., Reggiori, F., Kurth, I., Hubner, C. A., Dikic, I. Regulation of endoplasmic reticulum turnover by selective autophagy. Nature 522: 354-358, 2015. 3. Kurth, I., Pamminger, T., Hennings, J. C., Soehendra, D., Huebner, A. K., Rotthier, A., Baets, J., Senderek, J., Topaloglu, H., Farrell, S. A., Nurnberg, G., Nurnberg, P., De Jonghe, P., Gal, A., Kaether, C., Timmerman, V., Hubner, C. A. Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy. Nature Genet. 41: 1179-1181, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))
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别名
- RETREG1
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背景
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Synonyms: Protein Bop, BH3-only protein, Retrotransposon Gag-like protein 10, RTL10, BOP, C22orf29
Tissue Specificity: Ubiquitously expressed.
Background: The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 55 kDa
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基因ID
- 54463
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UniProt
- Q9H6L5
抗原
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