Erythrocyte Ankyrin 抗体 (AA 1300-1844)
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Quick Overview for Erythrocyte Ankyrin 抗体 (AA 1300-1844) (ABIN7599957)
抗原
See all Erythrocyte Ankyrin (ANK1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1300-1844
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原理
- Anti-Ankyrin erythroid/ANK/ANK1 Antibody (monoclonal, 5H2E8)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Ankyrin erythroid/ANK/ANK1 Antibody (monoclonal, 5H2E8) (ABIN7599957). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Ankyrin erythroid/ANK/ANK1 recombinant protein (Position: N1300-Q1844).
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亚型
- IgG2a
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anti-Ankyrin 1, Erythrocytic (ANK1) (C-Term) antibody
ANK1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibodyANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 unconjugated
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (HRP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 HRP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (FITC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 FITC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Biotin)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Biotin
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PE)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PE
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (APC)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 APC
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (PerCP)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 PerCP
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 488)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 488
anti-Ankyrin 1, Erythrocytic (ANK1) (AA 1-1881) antibody (Atto 594)ANK1 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S388A-10 Atto 594
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))
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别名
- ANK1
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背景
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Synonyms: Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, Chromatin assembly factor I p48 subunit, CAF-I 48 kDa subunit, CAF-I p48, Nucleosome-remodeling factor subunit RBAP48, Retinoblastoma-binding protein 4, RBBP-4, Retinoblastoma-binding protein p48, RBBP4, RBAP48
Background: Ankyrin 1, erythrocytic, also known as ANK1, is a protein that in humans is encoded by the ANK1 gene. Ankyrins are a family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats, a central region with a highly conserved spectrin binding domain, and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described. Truncated muscle-specific isoforms of ankyrin 1 resulting from usage of an alternate promoter have also been identified.
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分子量
- 206 kDa
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基因ID
- 286
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UniProt
- P16157
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途径
- Synaptic Membrane
抗原
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