ERAP2 抗体 (AA 13-960)
Quick Overview for ERAP2 抗体 (AA 13-960) (ABIN7599949)
抗原
See all ERAP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 13-960
-
原理
- Anti-ERAP2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-ERAP2 Antibody Picoband® (ABIN7599949). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human ERAP2 recombinant protein (Position: K13-T960).
-
亚型
- IgG
-
-
anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 1-350) antibody
ERAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 406-522) antibodyERAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (N-Term) antibodyERAP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 1-170) antibodyERAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) (AA 41-271) antibodyERAP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cagliani, R., Riva, S., Biasin, M., Fumagalli, M., Pozzoli, U., Lo Caputo, S., Mazzotta, F., Piacentini, L., Bresolin, N., Clerici, M., Sironi, M. Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection. Hum. Molec. Genet. 19: 4705-4714, 2010. 2. Saveanu, L., Carroll, O., Lindo, V., Del Val, M., Lopez, D., Lepelletier, Y., Greer, F., Schomburg, L., Fruci, D., Niedermann, G., van Endert, P. M. Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nature Immun. 6: 689-697, 2005. 3. Tanioka, T., Hattori, A., Masuda, S., Nomura, Y., Nakayama, H., Mizutani, S., Tsujimoto, M. Human leukocyte-derived arginine aminopeptidase: the third member of the oxytocinase subfamily of aminopeptidases. J. Biol. Chem. 278: 32275-32283, 2003. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
-
别名
- ERAP2
-
背景
-
Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29
Tissue Specificity: Brain.
Background: Endoplasmic reticulum aminopeptidase 2 is a protein that in humans is encoded by the ERAP2 gene. This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.
-
分子量
- 110 kDa
-
基因ID
- 64167
-
UniProt
- Q6P179
抗原
-
