MVK 抗体 (AA 13-394)
Quick Overview for MVK 抗体 (AA 13-394) (ABIN7599941)
抗原
See all MVK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-394
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原理
- Anti-MVK Antibody Picoband®
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产品特性
- Anti-MVK Antibody Picoband® (ABIN7599941). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MVK recombinant protein (Position: K13-D394). Human MVK shares 80.8% and 81.4% amino acid (aa) sequence identity with mouse and rat MVK, respectively.
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anti-Mevalonate Kinase (MVK) (AA 297-396) antibody
MVK 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-Mevalonate Kinase (MVK) (AA 297-396) antibodyMVK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) antibodyMVK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 1-396) antibodyMVK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) antibodyMVK 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 179-228) antibodyMVK 适用: 人, 小鼠, 猴, Cow, 犬, 兔, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (AA 107-156) antibodyMVK 适用: 人, 小鼠, 大鼠, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Mevalonate Kinase (MVK) (Internal Region) antibodyMVK 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Balgobind, B., Wittebol-Post, D., Frenkel, J. Retinitis pigmentosa in mevalonate kinase deficiency. J. Inherit. Metab. Dis. 28: 1143-1145, 2005. 2. Brito, T., Banganho, D., Pedrosa, C., Neves, J. F. Homozygous V377I mutation causing mevalonate kinase. BMJ Case Rep. 15: e249135, 2022. 3. Cuisset, L., Drenth, J. P. H., Simon, A., Vincent, M. F., van der Velde Visser, S., van der Meer, J. W. M., Grateau, G., Delpech, M., International Hyper-IgD Study Group. Molecular analysis of MVK mutations and enzymatic activity in hyper-IgD and periodic fever syndrome. Europ. J. Hum. Genet. 9: 260-266, 2001. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MVK (Mevalonate Kinase (MVK))
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别名
- MVK
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背景
- This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants.
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分子量
- 42 kDa
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基因ID
- 4598
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UniProt
- Q03426
抗原
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