PDXK 抗体 (AA 13-280)
Quick Overview for PDXK 抗体 (AA 13-280) (ABIN7599932)
抗原
See all PDXK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-280
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原理
- Anti-PDXK Antibody Picoband®
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交叉反应 （详细）
- No cross reactivity with other proteins.
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产品特性
- Anti-PDXK Antibody Picoband® (ABIN7599932). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PDXK recombinant protein (Position: H13-E280). Human PDXK shares 85.4% and 85.1% amino acid (aa) sequence identity with mouse and rat PDXK, respectively.
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亚型
- IgG
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anti-Pyridoxal Kinase (PDXK) (AA 29-253) antibody
PDXK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 29-285) antibodyPDXK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 35-251) antibodyPDXK 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5H5 unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 51-160) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Pyridoxal Kinase (PDXK) antibodyPDXK 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibodyPDXK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chelban, V., Wilson, M. P., Chardon, J. W., Vandrovcova, J., Zanetti, M. N., Zamba-Papanicolaou, E., Efthymiou, S., Pope, S., Conte, M. R., Abis, G., Liu, Y.-T., Tribollet, E., and 26 others. PDXK mutations cause polyneuropathy responsive to pyridoxal 5-prime-phosphate supplementation. Ann. Neurol. 86: 225-240, 2019. 2. Chern, C. J., Beutler, E. Biochemical and electrophoretic studies of erythrocyte pyridoxine kinase in white and black Americans. Am. J. Hum. Genet. 28: 9-17, 1976. 3. Gachon, F., Fonjallaz, P., Damiola, F., Gos, P., Kodama, T., Zakany, J., Duboule, D., Petit, B., Tafti, M., Schibler, U. The loss of circadian PAR bZip transcription factors results in epilepsy. Genes Dev. 18: 1397-1412, 2004. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PDXK (Pyridoxal Kinase (PDXK))
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别名
- PDXK
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背景
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Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity: Expressed in all tissues.
Background: Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene. The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
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分子量
- 35 kDa
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基因ID
- 8566
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UniProt
- O00764
抗原
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