VWF 抗体 (AA 1287-2770)
Quick Overview for VWF 抗体 (AA 1287-2770) (ABIN7599909)
抗原
See all VWF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1287-2770
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原理
- Anti-Von Willebrand Factor/VWF Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Von Willebrand Factor/VWF Antibody Picoband® (ABIN7599909). Tested in ELISA, IHC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Von Willebrand Factor/VWF recombinant protein (Position: R1287-Q2770).
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亚型
- IgG
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anti-Von Willebrand Factor (VWF) (AA 1498-1665) antibody
VWF 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 269-367) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VWF-1465 unconjugated
anti-Von Willebrand Factor (VWF) (AA 50-150) antibodyVWF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1304-1452) antibodyVWF 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 2535-2813) antibodyVWF 适用: 人 WB, IHC, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) antibodyVWF 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 907CT12-1-9 unconjugated
anti-Von Willebrand Factor (VWF) (AA 351-450) antibodyVWF 适用: 人, 大鼠, 小鼠 FACS, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 49-230) antibodyVWF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Von Willebrand Factor (VWF) (AA 1815-1939) antibodyVWF 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal VWF-1859R unconjugated Recombinant Antibody
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应用备注
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Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Sadler JE (1998). "Biochemistry and genetics of von Willebrand factor". Annu. Rev. Biochem. 67: 395-424. 2. Ginsburg, D., Handin, R. I., Bonthron, D. T., Donlon, T. A., Bruns, G. A. P., Latt, S. A., Orkin, S. H. Human von Willebrand factor (VWF): isolation of complementary DNA (cDNA) clones and chromosomal localization. Science 228: 1401-1406, 1985. 3. Sporn, L. A., Marder, V. J., Wagner, D. D. Von Willebrand factor released from Weibel-Palade bodies binds more avidly to extracellular matrix than that secreted constitutively. Blood 69: 1531-1534, 1987. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- VWF (Von Willebrand Factor (VWF))
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别名
- VWF
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背景
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Synonyms: Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, Forkhead box protein A1, Transcription factor 3A, TCF-3A, FOXA1, HNF3A, TCF3A
Tissue Specificity: Highly expressed in prostate and ESR1-positive breast tumors. Overexpressed in esophageal and lung adenocarcinomas.
Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.
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分子量
- 49 kDa
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基因ID
- 7450
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UniProt
- P04275
抗原
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