LRPPRC 抗体 (AA 1281-1394)
Quick Overview for LRPPRC 抗体 (AA 1281-1394) (ABIN7599908)
抗原
See all LRPPRC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1281-1394
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原理
- Anti-LRPPRC/GP130 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-LRPPRC/ Antibody Picoband® (ABIN7599908). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human LRPPRC/GP130 recombinant protein (Position: A1281-S1394).
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亚型
- IgG
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anti-Leucine-Rich PPR-Motif Containing (LRPPRC) (AA 1041-1394) antibody
LRPPRC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich PPR-Motif Containing (LRPPRC) (AA 901-1036) antibodyLRPPRC 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich PPR-Motif Containing (LRPPRC) antibodyKO Validated LRPPRC 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich PPR-Motif Containing (LRPPRC) (Internal Region) antibodyLRPPRC 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich PPR-Motif Containing (LRPPRC) (AA 847-876) antibodyLRPPRC 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53981 unconjugated
anti-Leucine-Rich PPR-Motif Containing (LRPPRC) (AA 1203-1236) antibodyLRPPRC 适用: 人 WB 宿主: 兔 Polyclonal RB55073 unconjugated
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Harmel, J., Ruzzenente, B., Terzioglu, M., Spahr, H., Falkenberg, M., Larsson, N.-G. The leucine-rich pentatricopeptide repeat-containing protein (LRPPRC) does not activate transcription in mammalian mitochondria. J. Biol. Chem. 288: 15510-15519, 2013. 2. Hou, J., Wang, F., McKeehan, W. L. Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2). In Vitro Cell Dev. Biol. Anim. 30A: 111-114, 1994. 3. Liu, L., McKeehan, W. L. Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggest roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. Genomics 79: 124-136, 2002. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))
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别名
- LRPPRC
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背景
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Synonyms: Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, GP130, LRPPRC, LRP130
Tissue Specificity: Expressed ubiquitously. Expression is highest in heart, skeletal muscle, kidney and liver, intermediate in brain, non-mucosal colon, spleen and placenta, and lowest in small intestine, thymus, lung and peripheral blood leukocytes.
Background: Leucine-rich PPR motif-containing protein, mitochondrial is a protein that in humans is encoded by the LRPPRC gene. It is mapped to 2p21. This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
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分子量
- 157 kDa
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基因ID
- 10128
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UniProt
- P42704
抗原
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