RAPGEF2 抗体 (AA 1266-1499)
Quick Overview for RAPGEF2 抗体 (AA 1266-1499) (ABIN7599891)
抗原
See all RAPGEF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1266-1499
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原理
- Anti-RAPGEF2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RAPGEF2 Antibody Picoband® (ABIN7599891). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAPGEF2 recombinant protein (Position: S1266-V1499).
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (AA 1398-1487) antibody
RAPGEF2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (C-Term) antibodyRAPGEF2 适用: 人, 小鼠, 犬, 马, 兔, 大鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (AA 1393-1498) antibodyRAPGEF2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (AA 1464-1498), (C-Term) antibodyRAPGEF2 适用: 人 WB 宿主: 兔 Polyclonal RB52925 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (AA 1398-1487) antibodyRAPGEF2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2) (Middle Region) antibodyRAPGEF2 适用: 人, 小鼠, 犬, 马, 兔, 大鼠, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. de Rooij, J., Boenink, N. M., van Triest, M., Cool, R. H., Wittinghofer, A., Bos, J. L. PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2. J. Biol. Chem. 274: 38125-38130, 1999. 2. Ishiura, H., Doi, K., Mitsui, J., Yoshimura, J., Matsukawa, M. K., Fujiyama, A., Toyoshima, Y., Kakita, A., Takahashi, H., Suzuki, Y., Sugano, S., Qu, W., and 55 others. Expansions of intronic TTTCA and TTTTA repeats in benign adult familial myoclonic epilepsy. Nature Genet. 50: 581-590, 2018. 3. Kawajiri, A., Itoh, N., Fukata, M., Nakagawa, M., Yamaga, M., Iwamatsu, A., Kaibuchi, K. Identification of a novel beta-catenin-interacting protein. Biochem. Biophys. Res. Commun. 273: 712-717, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))
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别名
- RAPGEF2
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背景
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Synonyms: Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.
Background: Rap guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the RAPGEF2 gene. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
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分子量
- 200-220 kDa
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基因ID
- 9693
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UniProt
- Q9Y4G8
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途径
- Neurotrophin Signaling Pathway
抗原
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