P-Cadherin 抗体 (AA 126-336)
Quick Overview for P-Cadherin 抗体 (AA 126-336) (ABIN7599888)
抗原
See all P-Cadherin (CDH3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 126-336
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原理
- Anti-P-Cadherin-3 CDH3-Antibody Picoband® (monoclonal, 3C9)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-P-Cadherin-3 CDH3-Antibody Picoband® (monoclonal, 3C9) (ABIN7599888). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human P cadherin recombinant protein (Position: Q126-H336).
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亚型
- IgG2b
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anti-P-Cadherin (CDH3) (AA 371-660) antibody
CDH3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (N-Term) antibodyCDH3 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 625-725) antibodyCDH3 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 24-350) antibodyCDH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (C-Term) antibodyCDH3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 117-360) antibodyCDH3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 1-829) antibodyCDH3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 187-236) antibodyCDH3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-P-Cadherin (CDH3) (AA 612-626), (Middle Region) antibodyCDH3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human1. Kaupmann K, Becker-Follmann J, Scherer G, Jockusch H, Starzinski-Powitz A (Dec 1992). "The gene for the cell adhesion molecule M-cadherin maps to mouse chromosome 8 and human chromosome 16q24.1-qter and is near the E-cadherin (uvomorulin) locus in both species". Genomics 14 (2): 488-90. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- P-Cadherin (CDH3)
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别名
- CDH3
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背景
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Synonyms: Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP
Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
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分子量
- 120 kDa
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基因ID
- 1001
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UniProt
- P22223
抗原
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