EDEM1 抗体 (AA 124-657)
Quick Overview for EDEM1 抗体 (AA 124-657) (ABIN7599876)
抗原
See all EDEM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-657
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原理
- Anti-EDEM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-EDEM1 Antibody Picoband® (ABIN7599876). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human EDEM1 recombinant protein (Position: P124-I657). Human EDEM1 shares 96.6% amino acid (aa) sequence identity with mouse EDEM1.
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亚型
- IgG
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 46-128) antibodyEDEM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (C-Term) antibodyEDEM1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 适用: 人, 小鼠, Cow, 兔, 猴, Pig, 豚鼠, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Hosokawa, N., Wada, I., Hasegawa, K., Yorihuzi, T., Tremblay, L. O., Herscovics, A., Nagata, K. A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. EMBO Rep. 2: 415-422, 2001. 2. Molinari, M., Calanca, V., Galli, C., Lucca, P., Paganetti, P. Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. Science 299: 1397-1400, 2003. 3. Nagase, T., Seki, N., Ishikawa, K., Ohira, M., Kawarabayasi, Y., Ohara, O., Tanaka, A., Kotani, H., Miyajima, N., Nomura, N. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res. 3: 321-329, 1996. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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别名
- EDEM1
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背景
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Synonyms: EDEM1, EDEM, KIAA0212, ER degradation-enhancing alpha-mannosidase-like protein 1
Background: Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol, protein targeting to ER, and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment.
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分子量
- 66 kDa
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基因ID
- 9695
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UniProt
- Q92611
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途径
- ER-Nucleus Signaling
抗原
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