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CPS1 抗体 (AA 124-379)

This anti-CPS1 antibody is a 兔 多克隆 antibody detecting CPS1 in WB, ELISA, IHC, IF, ICC 和 FACS. Suitable for 人, 大鼠, 小鼠 和 猴.
产品编号 ABIN7599871
发货至: 中国

Quick Overview for CPS1 抗体 (AA 124-379) (ABIN7599871)

抗原

See all CPS1 抗体
CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

适用

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人, 大鼠, 小鼠, 猴

宿主

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克隆类型

  • 46
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多克隆

标记

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This CPS1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 124-379

    原理

    Anti-CPS1 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-CPS1 Antibody Picoband® (ABIN7599871). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CPS1 recombinant protein (Position: N124-E379).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Adcock, M. W., Ledbetter, D. H., O'Brien, W. E. Analysis of mammalian carbamyl phosphate synthetase I utilizing cDNA clones from human and rat liver. (Abstract) Fed. Proc. 43: 1726, 1984. 2. Adcock, M. W., O'Brien, W. E. Molecular cloning of cDNA for rat and human carbamyl phosphate synthetase I. J. Biol. Chem. 259: 13471-13476, 1984. 3. Aoshima, T., Kajita, M., Sekido, Y., Kikuchi, S., Yasuda, I., Saheki, T., Watanabe, K., Shimokata, K., Niwa, T. Novel mutations (H337R and 238-362del) in the CPS1 gene cause carbamoyl phosphate synthetase I deficiency. Hum. Hered. 52: 99-101, 2001.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

    别名

    CPS1

    背景

    Synonyms: Wee1-like protein kinase, WEE1hu, Wee1A kinase, WEE1

    Tissue Specificity: Predominantly expressed in T-cells. Also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium.

    Background: Carbamoyl phosphate synthetase I is a ligase enzyme located in the mitochondria involved in the production of urea. The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.

    分子量

    165 kDa

    基因ID

    1373

    UniProt

    P31327

    途径

    Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process
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