SKAP2 抗体 (AA 124-208)
Quick Overview for SKAP2 抗体 (AA 124-208) (ABIN7599870)
抗原
See all SKAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-208
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原理
- Anti-SKAP2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SKAP2 Antibody Picoband® (ABIN7599870). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SKAP2 recombinant protein (Position: E124-E208).
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亚型
- IgG
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anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) antibody
SKAP2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (C-Term) antibodySKAP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (C-Term) antibodySKAP2 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-359) antibodySKAP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (C-Term) antibodyVerified SKAP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-120) antibodySKAP2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 1-120) antibodySKAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Src Kinase Associated Phosphoprotein 2 (SKAP2) (AA 135-184) antibodySKAP2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kouroku, Y., Soyama, A., Fujita, E., Urase, K., Tsukahara, T., Momoi, T. RA70 is a src kinase-associated protein expressed ubiquitously. Biochem. Biophys. Res. Commun. 252: 738-742, 1998. 2. Liu, J., Kang, H., Raab, M., da Silva, A. J., Kraeft, S.-K., Rudd, C. E. FYB (FYN binding protein) serves as a binding partner for lymphoid protein and FYN kinase substrate SKAP55 and a SKAP55-related protein in T cells. Proc. Nat. Acad. Sci. 95: 8779-8784, 1998. 3. Marie-Cardine, A., Verhagen, A. M., Eckerskorn, C., Schraven, B. SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55. FEBS Lett. 435: 55-60, 1998. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))
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别名
- SKAP2
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背景
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Synonyms: ELAV-like protein 2, ELAV-like neuronal protein 1, Hu-antigen B, HuB, Nervous system-specific RNA-binding protein Hel-N1, ELAVL2, HUB
Tissue Specificity: Brain, neural-specific.
Background: Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 41 kDa
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基因ID
- 8935
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UniProt
- O75563
抗原
-
