PATL2 抗体 (AA 123-411)
Quick Overview for PATL2 抗体 (AA 123-411) (ABIN7599862)
抗原
See all PATL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-411
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原理
- Anti-PATL2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-PATL2 Antibody Picoband® (ABIN7599862). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PATL2 recombinant protein (Position: Q123-Q411).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chen, B., Zhang, Z., Sun, X., Kuang, Y., Mao, X., Wang, X., Yan, Z., Li, B., Xu, Y., Yu, M., Fu, J., Mu, J., Zhou, Z., Li, Q., Jin, L., He, L., Sang, Q., Wang, L. Biallelic mutations in PATL2 cause female infertility characterized by oocyte maturation arrest. Am. J. Hum. Genet. 101: 609-615, 2017. 2. Maddirevula, S., Coskun, S., Alhassan, S., Elnour, A., Alsaif, H. S., Ibrahim, N., Abdulwahab, F., Arold, S. T., Alkuraya, F. S. Female infertility caused by mutations in the oocyte-specific translational repressor PATL2. Am. J. Hum. Genet. 101: 603-608, 2017. 3. Scheller, N., Resa-Infante, P., de la Luna, S., Galao, R. P., Albrecht, M., Kaestner, L., Lipp, P., Lengauer, T., Meyerhans, A., Diez, J. Identification of PatL1, a human homolog to yeast P body component Pat1. Biochim. Biophys. Acta 1773: 1786-1792, 2007. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PATL2 (Protein Associated with Topoisomerase II Homolog 2 (PATL2))
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别名
- PATL2
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背景
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Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: Predicted to enable RNA binding activity. Predicted to be involved in P-body assembly and deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to act upstream of or within negative regulation of cytoplasmic mRNA processing body assembly. Located in cytoplasm.
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分子量
- 59 kDa
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基因ID
- 197135
抗原
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