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IMPG2 抗体 (AA 122-152)

This anti-IMPG2 antibody is a 兔 多克隆 antibody detecting IMPG2 in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7599848
发货至: 中国

Quick Overview for IMPG2 抗体 (AA 122-152) (ABIN7599848)

抗原

See all IMPG2 抗体
IMPG2 (Interphotoreceptor Matrix Proteoglycan 2 (IMPG2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IMPG2 antibody is un-conjugated

应用范围

ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 4
    • 2
    • 1
    AA 122-152

    原理

    Anti-IMPG2 Antibody Picoband®

    交叉反应 (详细)

    No cross reactivity with other proteins.

    产品特性

    Anti-IMPG2 Antibody Picoband® (ABIN7599848). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human TXNIP recombinant protein (Position: D122-N152). Human TXNIP shares 93.5% amino acid (aa) sequence identity with both mouse and rat TXNIP.

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Acharya, S., Foletta, V. C., Lee, J. W., Rayborn, M. E., Rodriguez, I. R., Young, W. S., III, Hollyfield, J. G. SPACRCAN, a novel human interphotoreceptor matrix hyaluronan-binding proteoglycan synthesized by photoreceptors and pinealocytes. J. Biol. Chem. 275: 6945-6955, 2000. 2. Bandah-Rozenfeld, D., Collin, R. W. J., Banin, E., van den Born, I., Coene, K. L. M., Siemiatkowska, A. M., Zelinger, L., Khan, M. I., Lefeber, D. J., Erdinest, I., Testa, F., Simonelli, F., and 9 others. Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa. Am. J. Hum. Genet. 87: 199-208, 2010. 3. Brandl, C., Schulz, H. L., Issa, P. C., Birtel, J., Bergholz, R., Lange, C., Dahlke, C., Zobor, D., Weber, B. H. F., Stohr, H. Mutations in the genes for interphotoreceptor matrix proteoglycans, IMPG1 and IMPG2, in patients with vitelliform macular lesions. Genes (Basel) 8: 170, 2017.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • 抗原

    IMPG2 (Interphotoreceptor Matrix Proteoglycan 2 (IMPG2))

    别名

    IMPG2

    背景

    Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

    Tissue Specificity: Expressed in all tissues.

    Background: The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.

    分子量

    150 kDa

    基因ID

    50939
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