IQSEC2 抗体 (AA 122-1396)
Quick Overview for IQSEC2 抗体 (AA 122-1396) (ABIN7599847)
抗原
See all IQSEC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 122-1396
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原理
- Anti-IQSEC2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IQSEC2 Antibody Picoband® (ABIN7599847). Tested in WB, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human IQSEC2 recombinant protein (Position: A122-M1396). Human IQSEC2 shares 98.2% amino acid (aa) sequence identity with mouse IQSEC2.
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亚型
- IgG
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anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 451-484) antibody
IQSEC2 适用: 人 WB 宿主: 兔 Polyclonal RB52674 unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 1-949) antibodyIQSEC2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-IQ Motif and Sec7 Domain 2 (IQSEC2) (AA 351-400) antibodyIQSEC2 适用: 小鼠, 人, 大鼠, Cow, 豚鼠, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL
1. de Vries, B. B. A., Breedveld, G. J., Deelen, W. H., Niermeijer, M. F., Heutink, P., Breuning, M. H. Another family with nonspecific X-linked mental retardation (MRX78) maps to Xp11.4-p11.23. Am. J. Med. Genet. 111: 443-445, 2002. Note: Erratum: Am. J. Med. Genet. 113: 391 only 2002. 2. Filippova, G. N., Cheng, M. K., Moore, J. M., Truong, J.-P., Hu, Y. J., Nguyen, D. K., Tsuchiya, K. D., Disteche, C. M. Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development. Dev. Cell 8: 31-42, 2005. 3. Gedeon, A., Kerr, B., Mulley, J., Turner, G. Pericentromeric genes for non-specific X-linked mental retardation (MRX). Am. J. Med. Genet. 51: 553-564, 1994. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- IQSEC2 (IQ Motif and Sec7 Domain 2 (IQSEC2))
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别名
- IQSEC2
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背景
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Synonyms: IQSEC2, KIAA0522, IQ motif and SEC7 domain-containing protein 2
Background: This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked cognitive disability. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 163 kDa
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基因ID
- 23096
抗原
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