PRMT7 抗体 (AA 121-526)
Quick Overview for PRMT7 抗体 (AA 121-526) (ABIN7599840)
抗原
See all PRMT7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-526
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原理
- Anti-PRMT7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PRMT7 Antibody Picoband® (ABIN7599840). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRMT7 recombinant protein (Position: K121-D526).
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 285-390) antibody
PRMT7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 1-692) antibodyPRMT7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 1-692) antibodyPRMT7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (Internal Region) antibodyPRMT7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (N-Term) antibodyPRMT7 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, Cow, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 660-692) antibodyPRMT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 1-30) antibodyPRMT7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) antibodyPRMT7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (AA 88-197) antibodyPRMT7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 7 (PRMT7) (Internal Region) antibodyVerified PRMT7 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Akawi, N., McRae, J., Ansari, M., Balasubramanian, M., Blyth, M., Brady, A. F., Clayton, S., Cole, T., Deshpande, C., Fitzgerald, T. W., Foulds, N., Francis, R., and 30 others. Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families. Nature Genet. 47: 1363-1369, 2015. 2. Birnbaum, R., Yosha-Orpaz, N., Yanoov-Sharav, M., Kidron, D., Gur, H., Yosovich, K., Lerman-Sagie, T., Malinger, G. Prenatal and postnatal presentation of PRMT7 related syndrome: expanding the phenotypic manifestations. Am. J. Med. Genet. 179A: 78-84, 2019. 3. Kernohan, K. D., McBride, A., Xi, Y., Martin, N., Schwartzentruber, J., Dyment, D. A., Majewski, J., Blaser, S. Care4Rare Canada Consortium, Boycott, K. M., Chitayat, D. Loss of the arginine methyltranserase (sic) PRMT7 causes syndromic intellectual disability with microcephaly and brachydactyly. Clin. Genet. 91: 708-716, 2017. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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别名
- PRMT7
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背景
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Synonyms: Serine protease HTRA3,3.4.21.-,High-temperature requirement factor A3,Pregnancy-related serine protease,HTRA3,PRSP,
Tissue Specificity: Widely expressed, with highest levels in both adult and fetal heart, ovary, uterus placenta, and bladder. In the endometrium, expressed in epithelial glands and the stroma. Also present in leukocytes. Isoform 1 is predominant in heart and skeletal muscle, whereas isoform 2 is predominant in placenta and kidney. .
Background: Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene. This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.
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分子量
- 78 kDa
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基因ID
- 54496
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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