CD79a 抗体 (AA 121-226)
Quick Overview for CD79a 抗体 (AA 121-226) (ABIN7599837)
抗原
See all CD79a (CD79A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 121-226
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原理
- Anti-CD79a Antibody Picoband® (monoclonal, 4G4)
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD79a Antibody Picoband® (monoclonal, 4G4) (ABIN7599837). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CD79a recombinant protein (Position: T121-P226). Human CD79a shares 91% amino acid (aa) sequence identity with mouse CD79a.
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亚型
- IgG1
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anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 30-193) antibody
CD79A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 兔 Monoclonal IGA-1790R unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 猴 FACS, IF, WB, IHC, StM 宿主: 小鼠 Monoclonal JCB117-HM47-A9 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 33-145) antibodyCD79A 适用: 人 IF, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) antibodyCD79A 适用: 人 FACS, IF, IHC, StM 宿主: 小鼠 Monoclonal rIGA-764 unconjugated Recombinant Antibody
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibody (FITC)CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, Opossum ICFC 宿主: 小鼠 Monoclonal HM57 FITC
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, 犬, Non-Human Primate FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal HM47 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 202-216) antibodyCD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, Opossum FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal HM57 unconjugated
anti-B-cell antigen receptor complex-associated protein alpha chain (CD79A) (AA 208-222) antibody (PE)CD79A 适用: 人, 小鼠, 大鼠, Cow, Pig, 小鸡, 兔, 马, 豚鼠, 犬, Non-Human Primate ICFC 宿主: 小鼠 Monoclonal HM47 PE
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M (2002). "B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta". J. Immunol. 169 (2): 865-72. 2. Minegishi Y, Coustan-Smith E, Rapalus L, Ersoy F, Campana D, Conley ME (1999). "Mutations in Igalpha (CD79a) result in a complete block in B-cell development.". The Journal of Clinical Investigation 104 (8): 1115-21. 3. Wang Y, Kanegane H, Sanal O, Tezcan I, Ersoy F, Futatani T, Miyawaki T (2002). "Novel Ig a (CD79a) gene mutation in a Turkish patient with B cell-deficient agammaglobulinemia". American Journal of Medical Genetics 336: 333-336. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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别名
- CD79A
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背景
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Synonyms: B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A, IGA, MB1
Tissue Specificity: B-cells.
Background: Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 19q13.2. CD79A is a membrane protein with an extracellular immunoglobulin domain, a single span transmembrane region and a short cytoplasmic domain. Genetic deletion of the transmembrane exon of CD79A results in loss of CD79A protein and a complete block of B cell development at the pro to pre B cell transition. Similarly, humans with homozygous splice variants in CD79A predicted to result in loss of the transmembrane region and a truncated or absent protein display agammaglobulinemia and no peripheral B cells.
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分子量
- 44 kDa
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基因ID
- 973
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UniProt
- P11912
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途径
- BCR Signaling
抗原
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