Angiomotin 抗体 (AA 12-622)
Quick Overview for Angiomotin 抗体 (AA 12-622) (ABIN7599826)
抗原
See all Angiomotin (AMOT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-622
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原理
- Anti-Angiomotin/AMOT Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Angiomotin/AMOT Antibody Picoband® (ABIN7599826). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Angiomotin/AMOT recombinant protein (Position: T12-Q622).
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亚型
- IgG
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anti-Angiomotin (AMOT) (AA 1-300) antibody
AMOT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 545-620) antibodyAMOT 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 361-460) antibodyAMOT 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 361-460) antibodyAMOT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Angiomotin (AMOT) (AA 1-675) antibodyAMOT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 285-312) antibodyAMOT 适用: 人 WB 宿主: 兔 Polyclonal RB40425 unconjugated
anti-Angiomotin (AMOT) (AA 108-157) antibodyAMOT 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Cow, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 1-675) antibodyAMOT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Angiomotin (AMOT) (AA 1-675) antibodyAMOT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Angiomotin (AMOT) (pTyr599) antibodyAMOT 适用: 人 DB 宿主: 兔 Polyclonal RB41443 unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Aase, K., Ernkvist, M., Ebarasi, L., Jakobsson, L., Majumdar, A., Yi, C., Birot, O., Ming, Y., Kvanta, A., Edholm, D., Aspenstrom, P., Kissil, J., Claesson-Welsh, L., Shimono, A., Holmgren, L. Angiomotin regulates endothelial cell migration during embryonic angiogenesis. Genes Dev. 21: 2055-2068, 2007. 2. Bratt, A., Wilson, W. J., Troyanovsky, B., Aase, K., Kessler, R., Van Meir, E. G., Holmgren, L. Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains. Gene 298: 69-77, 2002. Note: Erratum: Gene 310: 221 only, 2003. 3. Kikuno, R., Nagase, T., Ishikawa, K., Hirosawa, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 6: 197-205, 1999. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Angiomotin (AMOT)
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别名
- AMOT
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背景
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Synonyms: Endothelial cell-specific molecule 1, ESM-1, ESM1
Tissue Specificity: Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Background: Angiomotin (AMOT) is a protein that in humans is encoded by the AMOT gene. This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 140 kDa
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基因ID
- 154796
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途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
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