PRMT3 抗体 (AA 12-514)
Quick Overview for PRMT3 抗体 (AA 12-514) (ABIN7599822)
抗原
See all PRMT3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-514
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原理
- Anti-PRMT3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-PRMT3 Antibody Picoband® (ABIN7599822). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human PRMT3 recombinant protein (Position: R12-S514).
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亚型
- IgG
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anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 311-529) antibody
PRMT3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 460-491) antibodyPRMT3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 142-173) antibodyPRMT3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 41-139) antibodyPRMT3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 41-139) antibodyPRMT3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 1-220) antibodyPRMT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 460-491), (C-Term) antibodyPRMT3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0115 unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 142-173), (N-Term) antibodyPRMT3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0029 unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) antibodyPRMT3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Arginine Methyltransferase 3 (PRMT3) (AA 468-421) antibodyVerified PRMT3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Tang, J., Gary, J. D., Clarke, S., Herschman, H. R. PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation. J. Biol. Chem. 273: 16935-16945, 1998. 2. Wolf, S. S. The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans. Cell. Molec. Life Sci. 66: 2109-2121, 2009. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))
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别名
- PRMT3
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背景
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Synonyms: N-alpha-acetyltransferase 15, NatA auxiliary subunit,Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100,NAA15,GA19, NARG1, NATH, TBDN100,
Tissue Specificity: Expressed at high levels in testis and in ocular endothelial cells. Also found in brain (corpus callosum), heart, colon, bone marrow and at lower levels in most adult tissues, including thyroid, liver, pancreas, mammary and salivary glands, lung, ovary, urogenital system and upper gastrointestinal tract. Overexpressed in gastric cancer, in papillary thyroid carcinomas and in a Burkitt lymphoma cell line (Daudi). Specifically suppressed in abnormal proliferating blood vessels in eyes of patients with proliferative diabetic retinopathy. .
Background: Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene. This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts on 40S ribosomal protein S2 (rpS2), which is its major in-vivo substrate, and is involved in the proper maturation of the 80S ribosome. Alternative splicing results in multiple transcript variants.
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分子量
- 60-70 kDa
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基因ID
- 10196
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UniProt
- O60678
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途径
- Protein targeting to Nucleus
抗原
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