Tricellulin 抗体 (AA 12-496)
Quick Overview for Tricellulin 抗体 (AA 12-496) (ABIN7599821)
抗原
See all Tricellulin (MARVELD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-496
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原理
- Anti-MARVELD2 Antibody Picoband®
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产品特性
- Anti-MARVELD2 Antibody Picoband® (ABIN7599821). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MARVELD2 recombinant protein (Position: R12-H496). Human MARVELD2 shares 87% amino acid (aa) sequence identity with mouse MARVELD2.
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anti-Tricellulin (MARVELD2) (AA 251-300) antibody
MARVELD2 适用: 人, 小鼠, Cow, 犬, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Tricellulin (MARVELD2) (AA 200-300) antibodyMARVELD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tricellulin (MARVELD2) (AA 1-195) antibodyMARVELD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tricellulin (MARVELD2) (AA 386-415), (C-Term) antibodyMARVELD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24717 unconjugated
anti-Tricellulin (MARVELD2) (AA 393-423), (C-Term) antibodyMARVELD2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chishti, M. S., Bhatti, A., Tamim, S., Lee, K., McDonald, M.-L., Leal, S. M., Ahmad, W. Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families. J. Hum. Genet. 53: 101-105, 2008. 2. Ikenouchi, J., Furuse, M., Furuse, K., Sasaki, H., Tsukita, S., Tsukita, S. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J. Cell Biol. 171: 939-945, 2005. 3. Riazuddin, S., Ahmed, Z. M., Fanning, A. S., Lagziel, A., Kitajiri, S., Ramzan, K., Khan, S. N., Chattaraj, P., Friedman, P. L., Anderson, J. M., Belyantseva, I. A., Forge, A., Riazuddin, S., Friedman, T. B. Tricellulin is a tight-junction protein necessary for hearing. Am. J. Hum. Genet. 79: 1040-1051, 2006. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Tricellulin (MARVELD2)
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别名
- MARVELD2
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背景
- MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene. The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 64 kDa
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基因ID
- 153562
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UniProt
- Q8N4S9
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途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
抗原
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