NSUN3 抗体 (AA 12-310)
Quick Overview for NSUN3 抗体 (AA 12-310) (ABIN7599814)
抗原
See all NSUN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 12-310
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原理
- Anti-NSUN3 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NSUN3 Antibody Picoband® (ABIN7599814). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human NSUN3 recombinant protein (Position: K12-E310).
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亚型
- IgG
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anti-NOP2/Sun Domain Family, Member 3 (NSUN3) (AA 143-192) antibody
NSUN3 适用: 人, 小鼠, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 3 (NSUN3) (AA 239-288) antibodyNSUN3 适用: 人, 小鼠, 犬, 兔, Cow, 豚鼠, 马, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 3 (NSUN3) (AA 1-120) antibodyNSUN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NOP2/Sun Domain Family, Member 3 (NSUN3) (C-Term) antibodyNSUN3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.25-0.5 μg/mL, Human, Monkey
Flow Cytometry (Fixed), 1-3 μg /1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Haag, S., Sloan, K. E., Ranjan, N., Warda, A. S., Kretschmer, J., Blessing, C., Hubner, B., Seikowski, J., Dennerlein, S., Rehling, P., Rodnina, M., Hobartner, C., Bohnsack, M. T. NSUN3 and ABH1 modify the wobble position of mt-tRNA(Met) to expand codon recognition in mitochondrial translation. EMBO J. 35: 2104-2119, 2016. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/25/2017. 3. Nakano, S., Suzuki, T., Kawarada, L., Iwata, H., Asano, K., Suzuki, T. NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNA(Met). Nature Chem. Biol. 12: 546-551, 2016. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NSUN3 (NOP2/Sun Domain Family, Member 3 (NSUN3))
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别名
- NSUN3
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背景
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Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489
Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.
Background: NSUN3 (NOL1/NOP2/Sun domain family, member 3), also known as MST077, is a 340 amino acid protein that belongs to the methyltransferase superfamily and is thought to function as an S-adenosyl-L-methionine-dependent methyltransferase. The gene encoding NSUN3 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3
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分子量
- 38 kDa
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基因ID
- 63899
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UniProt
- Q9H649
抗原
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