电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PARP9 抗体 (AA 117-824)

PARP9 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7599784
发货至: 中国
  • 抗原 See all PARP9 抗体
    PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 117-824
    适用
    人, 小鼠, 大鼠
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 9
    This PARP9 antibody is un-conjugated
    应用范围
    • 9
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-PARP9 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-PARP9 Antibody Picoband® (ABIN7599784). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human PARP9 recombinant protein (Position: R117-E824).
    亚型
    IgG
    Top Product
    Discover our top product PARP9 Primary Antibody
  • 应用备注
    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Aguiar, R. C. T., Takeyama, K., He, C., Kreinbrink, K., Shipp, M. A. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. J. Biol. Chem. 280: 33756-33765, 2005. 2. Aguiar, R. C. T., Yakushijin, Y., Kharbanda, S., Salgia, R., Fletcher, J. A., Shipp, M. A. BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration. Blood 96: 4328-4334, 2000. 3. Juszczynski, P., Kutok, J. L., Li, C., Mitra, J., Aguiar, R. C. T. BAL1 and BBAP are regulated by a gamma interferon-responsive biional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. Molec. Cell. Biol. 26: 5348-5359, 2006.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))
    别名
    PARP9 (PARP9 产品)
    背景

    Synonyms: PHD finger protein 21A; BHC80a; BRAF35-HDAC complex protein BHC80; PHF21A; BHC80; KIAA1696; BM-006

    Tissue Specificity: Highly expressed in brain. Expressed at much lower level in other tissues.

    Background: Poly (ADP-ribosyl)ation is a post-translational modification of proteins mediated by one of the 17 members of the poly (ADP-ribose) polymerases (PARP). PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFNγ, inducing the transcription of IFNγ-controlled genes.

    分子量
    96 kDa
    基因ID
    83666
You are here:
Chat with us!