PARP9 抗体 (AA 117-824)
Quick Overview for PARP9 抗体 (AA 117-824) (ABIN7599784)
抗原
See all PARP9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 117-824
-
原理
- Anti-PARP9 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-PARP9 Antibody Picoband® (ABIN7599784). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human PARP9 recombinant protein (Position: R117-E824).
-
亚型
- IgG
-
-
anti-Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9) (AA 144-193) antibody
PARP9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9) (AA 599-629) antibodyPARP9 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal RB14182 unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9) (AA 569-601), (C-Term) antibodyPARP9 适用: 小鼠 WB, EIA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9) (AA 441-470), (N-Term) antibodyPARP9 适用: 小鼠 WB 宿主: 兔 Polyclonal RB14180 unconjugated
anti-Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9) (N-Term) antibodyPARP9 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Aguiar, R. C. T., Takeyama, K., He, C., Kreinbrink, K., Shipp, M. A. B-aggressive lymphoma family proteins have unique domains that modulate transcription and exhibit poly(ADP-ribose) polymerase activity. J. Biol. Chem. 280: 33756-33765, 2005. 2. Aguiar, R. C. T., Yakushijin, Y., Kharbanda, S., Salgia, R., Fletcher, J. A., Shipp, M. A. BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration. Blood 96: 4328-4334, 2000. 3. Juszczynski, P., Kutok, J. L., Li, C., Mitra, J., Aguiar, R. C. T. BAL1 and BBAP are regulated by a gamma interferon-responsive biional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. Molec. Cell. Biol. 26: 5348-5359, 2006. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))
-
别名
- PARP9
-
背景
-
Synonyms: PHD finger protein 21A; BHC80a; BRAF35-HDAC complex protein BHC80; PHF21A; BHC80; KIAA1696; BM-006
Tissue Specificity: Highly expressed in brain. Expressed at much lower level in other tissues.
Background: Poly (ADP-ribosyl)ation is a post-translational modification of proteins mediated by one of the 17 members of the poly (ADP-ribose) polymerases (PARP). PARP-9 belongs to the subfamily of macroPARPs, associating one to three macro domains to the PARP domain. Overexpression of PARP-9 stimulates cell migration in vitro, suggesting a role for PARP-9 in the promotion of malignant B cell migration and dissemination in high risk DLBCL. PARP-9 is also likely a transcription coactivator, its overexpression in B lymphocytes, stimulated by IFNγ, inducing the transcription of IFNγ-controlled genes.
-
分子量
- 96 kDa
-
基因ID
- 83666
抗原
-
