CEP55 抗体 (AA 115-464)
Quick Overview for CEP55 抗体 (AA 115-464) (ABIN7599765)
抗原
See all CEP55 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 115-464
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原理
 - Anti-CEP55 Antibody Picoband®
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交叉反应 (详细)
 - No cross-reactivity with other proteins
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产品特性
 - Anti-CEP55 Antibody Picoband® (ABIN7599765). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - E.coli-derived human CEP55 recombinant protein (Position: E115-K464). Human CEP55 shares 76.3% and 78% amino acid (aa) sequence identity with mouse and rat CEP55, respectively.
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL
1. Bondeson, M.-L., Ericson, K., Gudmundsson, S., Ameur, A., Ponten, F., Wesstrom, J., Frykholm, C., Wilbe, M. A nonsense mutation in CEP55 defines a new locus for a Meckel-like syndrome, an autosomal recessive lethal fetal ciliopathy. Clin. Genet. 92: 510-516, 2017. 2. Chen, C.-H., Chien, C.-Y., Huang, C.-C., Hwang, C.-F., Chuang, H.-C., Fang, F.-M., Huang, H.-Y., Chen, C.-M., Liu, H.-L., Huang, C.-Y. F. Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity. Oncogene 28: 2723-2737, 2009. 3. Chen, C.-H., Lu, P.-J., Chen, Y.-C., Fu, S.-L., Wu, K.-J., Tsou, A.-P., Lee, Y.-C. G., Lin, T.-C. E., Hsu, S.-L., Lin, W.-J., Huang, C.-Y. F., Chou, C.-K. FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway. Oncogene 26: 4272-4283, 2007. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. 
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- CEP55 (Centrosomal Protein 55kDa (CEP55))
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别名
 - CEP55
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背景
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Synonyms: CEP55, C10orf3, URCC6, Centrosomal protein of 55 kDa, Cep55, Up-regulated in colon cancer 6
Background: Centrosomal protein of 55 kDa (Cep55), is a protein that in humans is encoded by the CEP55 gene. Enables identical protein binding activity. Involved in cranial skeletal system development, establishment of protein localization, and midbody abscission. Acts upstream of or within mitotic cytokinesis. Located in Flemming body and centrosome. Implicated in multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia and hydranencephaly.
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分子量
 - 54 kDa
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基因ID
 - 55165
 
抗原
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